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| U | Atlético Madrid | - | Sevilla FC | 1:2 (0:0) | ||
| R | Sevilla FC | - | Atlético Madrid | 3:1 (1:1) | ||
| U: 17.01.2018 19:00 | R: 23.01.2018 21:30 | Winnaars: Sevilla FC | ||||
| U | Valencia CF | - | Deportivo Alavés | 2:1 (0:0) | ||
| R | Deportivo Alavés | - | Valencia CF | 2:3 (0:0, 2:1, 2:1) d.p. | ||
| U: 17.01.2018 19:00 | R: 24.01.2018 19:00 | Winnaars: Valencia CF | ||||
| U | Espanyol | - | FC Barcelona | 1:0 (0:0) | ||
| R | FC Barcelona | - | Espanyol | 2:0 (2:0) | ||
| U: 17.01.2018 21:00 | R: 25.01.2018 21:30 | Winnaars: FC Barcelona | ||||
| U | CD Leganés | - | Real Madrid | 0:1 (0:0) | ||
| R | Real Madrid | - | CD Leganés | 1:2 (0:1) | ||
| U: 18.01.2018 21:30 | R: 24.01.2018 21:30 | Winnaars: CD Leganés | ||||
