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| U | Monarcas Morelia | - | CF Monterrey | 1:0 | ||
| R | CF Monterrey | - | Monarcas Morelia | 3:2 | ||
| U: 22.11.2017 17:00 | R: 25.11.2017 17:00 | Winnaars: Monarcas Morelia | ||||
| U | Deportivo Guadalajara | - | CF Pachuca | 3:1 | ||
| R | CF Pachuca | - | Deportivo Guadalajara | 1:3 | ||
| U: 22.11.2017 17:30 | R: 25.11.2017 16:30 | Winnaars: Deportivo Guadalajara | ||||
| U | Club Necaxa | - | Santos Laguna | 0:0 | ||
| R | Santos Laguna | - | Club Necaxa | 1:0 | ||
| U: 23.11.2017 16:00 | R: 26.11.2017 16:00 | Winnaars: Santos Laguna | ||||
| U | CF América | - | Pumas UNAM | 0:0 | ||
| R | Pumas UNAM | - | CF América | 0:0 | ||
| U: 23.11.2017 17:00 | R: 26.11.2017 19:45 | |||||
