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| 07.03.2008 | 18:00 | FC Augsburg | - | Bor. Mönchengladbach | 0:2 (0:1) | |
| 18:00 | 1. FC Kaiserslautern | - | SC Freiburg | 0:0 (0:0) | ||
| 18:00 | Alemannia Aachen | - | SpVgg Greuther Fürth | 2:5 (1:3) | ||
| 09.03.2008 | 14:00 | 1899 Hoffenheim | - | SC Paderborn 07 | 1:0 (0:0) | |
| 14:00 | 1. FC Köln | - | TuS Koblenz | 1:0 (0:0) | ||
| 14:00 | 1. FSV Mainz 05 | - | Kickers Offenbach | 1:0 (0:0) | ||
| 14:00 | FC Carl Zeiss Jena | - | SV Wehen Wiesbaden | 2:2 (2:0) | ||
| 14:00 | Erzgebirge Aue | - | VfL Osnabrück | 0:1 (0:0) | ||
| 10.03.2008 | 20:15 | FC St. Pauli | - | TSV 1860 München | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bor. Mönchengladbach | 23 | 12 | 8 | 3 | 45:26 | 19 | 44 |
| 2 |
|
1. FSV Mainz 05 | 23 | 11 | 7 | 5 | 38:22 | 16 | 40 |
| 3 |
|
SpVgg Greuther Fürth | 23 | 11 | 7 | 5 | 41:28 | 13 | 40 |
| 4 |
|
1899 Hoffenheim | 23 | 11 | 7 | 5 | 37:29 | 8 | 40 |
| 5 |
|
1. FC Köln | 23 | 11 | 6 | 6 | 41:30 | 11 | 39 |
| 6 |
|
SV Wehen Wiesbaden | 23 | 9 | 9 | 5 | 38:33 | 5 | 36 |
| 7 |
|
SC Freiburg | 23 | 9 | 9 | 5 | 32:27 | 5 | 36 |
| 8 |
|
TSV 1860 München | 23 | 8 | 10 | 5 | 31:23 | 8 | 34 |
| 9 |
|
Alemannia Aachen | 23 | 7 | 8 | 8 | 33:36 | -3 | 29 |
| 10 |
|
VfL Osnabrück | 23 | 7 | 7 | 9 | 32:41 | -9 | 28 |
| 11 |
|
FC Augsburg | 23 | 7 | 6 | 10 | 29:34 | -5 | 27 |
| 12 |
|
FC St. Pauli | 23 | 6 | 9 | 8 | 28:33 | -5 | 27 |
| 13 |
|
Kickers Offenbach | 23 | 6 | 8 | 9 | 26:39 | -13 | 26 |
| 14 |
|
TuS Koblenz | 23 | 7 | 9 | 7 | 28:31 | -3 | 24 |
| 15 |
|
Erzgebirge Aue | 23 | 6 | 4 | 13 | 30:39 | -9 | 22 |
| 16 |
|
1. FC Kaiserslautern | 23 | 4 | 9 | 10 | 22:27 | -5 | 21 |
| 17 |
|
FC Carl Zeiss Jena | 23 | 3 | 7 | 13 | 32:47 | -15 | 16 |
| 18 |
|
SC Paderborn 07 | 23 | 2 | 10 | 11 | 15:33 | -18 | 16 |
