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| 26.04.2019 | 18:30 | 1. FC Köln | - | SV Darmstadt 98 | 1:2 (0:1) | |
| 18:30 | FC Ingolstadt 04 | - | Dynamo Dresden | 1:0 (0:0) | ||
| 27.04.2019 | 13:00 | SV Sandhausen | - | Holstein Kiel | 3:2 (2:2) | |
| 13:00 | FC St. Pauli | - | Jahn Regensburg | 4:3 (1:2) | ||
| 13:00 | 1. FC Magdeburg | - | SpVgg Greuther Fürth | 2:1 (2:1) | ||
| 28.04.2019 | 13:30 | 1. FC Union Berlin | - | Hamburger SV | 2:0 (0:0) | |
| 13:30 | Erzgebirge Aue | - | VfL Bochum | 3:2 (2:1) | ||
| 13:30 | SC Paderborn 07 | - | 1. FC Heidenheim 1846 | 3:1 (0:0) | ||
| 29.04.2019 | 20:30 | MSV Duisburg | - | Arminia Bielefeld | 2:2 (1:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Köln | 31 | 18 | 5 | 8 | 76:41 | 35 | 59 |
| 2 |
|
SC Paderborn 07 | 31 | 15 | 9 | 7 | 71:44 | 27 | 54 |
| 3 |
|
1. FC Union Berlin | 31 | 13 | 14 | 4 | 48:29 | 19 | 53 |
| 4 |
|
Hamburger SV | 31 | 15 | 8 | 8 | 41:35 | 6 | 53 |
| 5 |
|
1. FC Heidenheim 1846 | 31 | 13 | 10 | 8 | 45:37 | 8 | 49 |
| 6 |
|
FC St. Pauli | 31 | 14 | 6 | 11 | 44:49 | -5 | 48 |
| 7 |
|
Holstein Kiel | 31 | 12 | 10 | 9 | 57:48 | 9 | 46 |
| 8 |
|
Jahn Regensburg | 31 | 11 | 12 | 8 | 47:46 | 1 | 45 |
| 9 |
|
Arminia Bielefeld | 31 | 10 | 10 | 11 | 46:50 | -4 | 40 |
| 10 |
|
SV Darmstadt 98 | 31 | 11 | 7 | 13 | 42:49 | -7 | 40 |
| 11 |
|
VfL Bochum | 31 | 10 | 9 | 12 | 43:46 | -3 | 39 |
| 12 |
|
SpVgg Greuther Fürth | 31 | 9 | 11 | 11 | 34:50 | -16 | 38 |
| 13 |
|
Erzgebirge Aue | 31 | 10 | 6 | 15 | 39:44 | -5 | 36 |
| 14 |
|
Dynamo Dresden | 31 | 9 | 9 | 13 | 36:43 | -7 | 36 |
| 15 |
|
SV Sandhausen | 31 | 8 | 10 | 13 | 40:45 | -5 | 34 |
| 16 |
|
1. FC Magdeburg | 31 | 6 | 12 | 13 | 32:45 | -13 | 30 |
| 17 |
|
FC Ingolstadt 04 | 31 | 7 | 8 | 16 | 35:51 | -16 | 29 |
| 18 |
|
MSV Duisburg | 31 | 5 | 10 | 16 | 34:58 | -24 | 25 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
