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|
| 14.01.2022 | 18:30 | Dynamo Dresden | - | Hamburger SV | 1:1 (0:1) | |
| 18:30 | Hansa Rostock | - | Hannover 96 | 0:1 (0:0) | ||
| 15.01.2022 | 13:30 | Werder Bremen | - | Fortuna Düsseldorf | 3:0 (0:0) | |
| 13:30 | 1. FC Nürnberg | - | SC Paderborn 07 | 1:2 (0:2) | ||
| 13:30 | FC St. Pauli | - | Erzgebirge Aue | 2:2 (1:1) | ||
| 20:30 | SV Darmstadt 98 | - | Karlsruher SC | 2:2 (0:1) | ||
| 16.01.2022 | 13:30 | FC Schalke 04 | - | Holstein Kiel | 1:1 (0:0) | |
| 13:30 | SV Sandhausen | - | Jahn Regensburg | 0:3 (0:2) | ||
| 13:30 | 1. FC Heidenheim 1846 | - | FC Ingolstadt 04 | 2:1 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC St. Pauli | 19 | 11 | 4 | 4 | 39:25 | 14 | 37 |
| 2 |
|
SV Darmstadt 98 | 19 | 11 | 3 | 5 | 43:22 | 21 | 36 |
| 3 |
|
1. FC Heidenheim 1846 | 19 | 10 | 3 | 6 | 25:25 | 0 | 33 |
| 4 |
|
Werder Bremen | 19 | 9 | 5 | 5 | 35:25 | 10 | 32 |
| 5 |
|
Hamburger SV | 19 | 7 | 10 | 2 | 32:19 | 13 | 31 |
| 6 |
|
FC Schalke 04 | 19 | 9 | 4 | 6 | 35:24 | 11 | 31 |
| 7 |
|
Jahn Regensburg | 19 | 9 | 4 | 6 | 38:28 | 10 | 31 |
| 8 |
|
SC Paderborn 07 | 19 | 8 | 6 | 5 | 33:22 | 11 | 30 |
| 9 |
|
1. FC Nürnberg | 19 | 8 | 6 | 5 | 28:23 | 5 | 30 |
| 10 |
|
Karlsruher SC | 19 | 6 | 8 | 5 | 33:30 | 3 | 26 |
| 11 |
|
Dynamo Dresden | 19 | 7 | 2 | 10 | 21:26 | -5 | 23 |
| 12 |
|
Hannover 96 | 19 | 6 | 5 | 8 | 15:27 | -12 | 23 |
| 13 |
|
Holstein Kiel | 19 | 5 | 7 | 7 | 24:31 | -7 | 22 |
| 14 |
|
Fortuna Düsseldorf | 19 | 5 | 5 | 9 | 23:28 | -5 | 20 |
| 15 |
|
Hansa Rostock | 19 | 5 | 5 | 9 | 21:32 | -11 | 20 |
| 16 |
|
SV Sandhausen | 19 | 4 | 5 | 10 | 20:39 | -19 | 17 |
| 17 |
|
Erzgebirge Aue | 19 | 3 | 6 | 10 | 17:32 | -15 | 15 |
| 18 |
|
FC Ingolstadt 04 | 19 | 2 | 4 | 13 | 15:39 | -24 | 10 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
