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| 05.05.2023 | 18:30 | Arminia Bielefeld | - | SpVgg Greuther Fürth | 1:1 (1:1) | |
| 18:30 | Hamburger SV | - | SC Paderborn 07 | 2:2 (1:1) | ||
| 06.05.2023 | 13:00 | Fortuna Düsseldorf | - | Holstein Kiel | 3:0 (3:0) | |
| 13:00 | Karlsruher SC | - | Hannover 96 | 2:1 (2:1) | ||
| 13:00 | Hansa Rostock | - | Jahn Regensburg | 2:0 (1:0) | ||
| 20:30 | SV Darmstadt 98 | - | FC St. Pauli | 0:3 (0:1) | ||
| 07.05.2023 | 13:30 | Eintracht Braunschweig | - | SV Sandhausen | 2:1 (0:0) | |
| 13:30 | 1. FC Heidenheim 1846 | - | 1. FC Magdeburg | 0:0 (0:0) | ||
| 13:30 | 1. FC Nürnberg | - | 1. FC Kaiserslautern | 3:3 (2:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SV Darmstadt 98 | 31 | 19 | 7 | 5 | 48:27 | 21 | 64 |
| 2 |
|
1. FC Heidenheim 1846 | 31 | 17 | 10 | 4 | 61:31 | 30 | 61 |
| 3 |
|
Hamburger SV | 31 | 17 | 6 | 8 | 62:43 | 19 | 57 |
| 4 |
|
FC St. Pauli | 31 | 15 | 8 | 8 | 50:35 | 15 | 53 |
| 5 |
|
Fortuna Düsseldorf | 31 | 16 | 5 | 10 | 54:40 | 14 | 53 |
| 6 |
|
SC Paderborn 07 | 31 | 15 | 6 | 10 | 63:39 | 24 | 51 |
| 7 |
|
1. FC Kaiserslautern (N) | 31 | 11 | 12 | 8 | 46:41 | 5 | 45 |
| 8 |
|
Karlsruher SC | 31 | 12 | 6 | 13 | 52:50 | 2 | 42 |
| 9 |
|
Hannover 96 | 31 | 11 | 7 | 13 | 44:46 | -2 | 40 |
| 10 |
|
Holstein Kiel | 31 | 10 | 10 | 11 | 48:55 | -7 | 40 |
| 11 |
|
1. FC Magdeburg (N) | 31 | 11 | 6 | 14 | 42:52 | -10 | 39 |
| 12 |
|
SpVgg Greuther Fürth (A) | 31 | 9 | 10 | 12 | 40:46 | -6 | 37 |
| 13 |
|
Eintracht Braunschweig (N) | 31 | 9 | 8 | 14 | 38:53 | -15 | 35 |
| 14 |
|
1. FC Nürnberg | 31 | 9 | 7 | 15 | 29:47 | -18 | 34 |
| 15 |
|
Hansa Rostock | 31 | 10 | 4 | 17 | 28:46 | -18 | 34 |
| 16 |
|
Arminia Bielefeld (A) | 31 | 8 | 6 | 17 | 46:55 | -9 | 30 |
| 17 |
|
Jahn Regensburg | 31 | 7 | 7 | 17 | 29:49 | -20 | 28 |
| 18 |
|
SV Sandhausen | 31 | 7 | 7 | 17 | 34:59 | -25 | 28 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
