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| 12.08.2022 | 18:30 | 1. FC Nürnberg | - | 1. FC Heidenheim 1846 | 0:3 (0:1) | |
| 18:30 | 1. FC Kaiserslautern | - | SC Paderborn 07 | 0:1 (0:0) | ||
| 13.08.2022 | 13:00 | Arminia Bielefeld | - | Hamburger SV | 0:2 (0:1) | |
| 13:00 | Holstein Kiel | - | Eintracht Braunschweig | 3:0 (1:0) | ||
| 13:00 | Karlsruher SC | - | SV Sandhausen | 3:2 (1:1) | ||
| 20:30 | SV Darmstadt 98 | - | Hansa Rostock | 4:0 (2:0) | ||
| 14.08.2022 | 13:30 | FC St. Pauli | - | 1. FC Magdeburg | 3:0 (2:0) | |
| 13:30 | Fortuna Düsseldorf | - | SpVgg Greuther Fürth | 2:2 (0:1) | ||
| 13:30 | Hannover 96 | - | Jahn Regensburg | 1:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Paderborn 07 | 4 | 3 | 0 | 1 | 11:4 | 7 | 9 |
| 2 |
|
1. FC Heidenheim 1846 | 4 | 3 | 0 | 1 | 7:1 | 6 | 9 |
| 3 |
|
SV Darmstadt 98 | 4 | 3 | 0 | 1 | 7:3 | 4 | 9 |
| 4 |
|
Hamburger SV | 4 | 3 | 0 | 1 | 5:1 | 4 | 9 |
| 5 |
|
Holstein Kiel | 4 | 2 | 2 | 0 | 9:5 | 4 | 8 |
| 6 |
|
Jahn Regensburg | 4 | 2 | 1 | 1 | 5:1 | 4 | 7 |
| 7 |
|
FC St. Pauli | 4 | 2 | 1 | 1 | 9:6 | 3 | 7 |
| 8 |
|
1. FC Kaiserslautern (N) | 4 | 2 | 1 | 1 | 6:5 | 1 | 7 |
|
Fortuna Düsseldorf | 4 | 2 | 1 | 1 | 6:5 | 1 | 7 | |
| 10 |
|
SV Sandhausen | 4 | 2 | 0 | 2 | 6:6 | 0 | 6 |
| 11 |
|
Hansa Rostock | 4 | 2 | 0 | 2 | 3:6 | -3 | 6 |
| 12 |
|
Hannover 96 | 4 | 1 | 1 | 2 | 6:8 | -2 | 4 |
| 13 |
|
1. FC Nürnberg | 4 | 1 | 1 | 2 | 4:6 | -2 | 4 |
| 14 |
|
Karlsruher SC | 4 | 1 | 1 | 2 | 6:11 | -5 | 4 |
| 15 |
|
SpVgg Greuther Fürth (A) | 4 | 0 | 3 | 1 | 5:7 | -2 | 3 |
| 16 |
|
1. FC Magdeburg (N) | 4 | 1 | 0 | 3 | 5:9 | -4 | 3 |
| 17 |
|
Arminia Bielefeld (A) | 4 | 0 | 0 | 4 | 2:9 | -7 | 0 |
| 18 |
|
Eintracht Braunschweig (N) | 4 | 0 | 0 | 4 | 0:9 | -9 | 0 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
