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| 26.03.2022 | 18:05 | Acassuso | - | Comunicaciones de Buenos Aires | 1:1 (1:1) | |
| 18:30 | Deportivo Merlo | - | Ituzaingó | 0:1 (0:0) | ||
| 19:30 | Argentino de Quilmes | - | Cañuelas | 0:1 (0:1) | ||
| 19:30 | Colegiales de Munro | - | CA Los Andes | 2:0 (0:0) | ||
| 19:30 | Talleres (RdE) | - | Fénix | 2:0 (1:0) | ||
| 19:30 | Defensores Unidos de Zárate | - | Atlético San Miguel | 2:1 (2:1) | ||
| 19:30 | Villa San Carlos | - | Armenio | 0:0 (0:0) | ||
| 19:30 | UAI Urquiza | - | Dock Sud | 3:2 (3:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Ituzaingó | 7 | 5 | 1 | 1 | 7:2 | 5 | 16 |
| 2 |
|
Comunicaciones de Buenos Aires | 7 | 4 | 2 | 1 | 11:4 | 7 | 14 |
| 3 |
|
Defensores Unidos de Zárate | 7 | 3 | 4 | 0 | 11:8 | 3 | 13 |
| 4 |
|
Armenio | 6 | 2 | 4 | 0 | 5:1 | 4 | 10 |
| 5 |
|
Fénix | 7 | 2 | 4 | 1 | 6:4 | 2 | 10 |
| 6 |
|
Cañuelas | 7 | 3 | 1 | 3 | 7:6 | 1 | 10 |
| 7 |
|
Colegiales de Munro | 6 | 2 | 2 | 2 | 9:8 | 1 | 8 |
| 8 |
|
Villa San Carlos | 7 | 2 | 2 | 3 | 6:6 | 0 | 8 |
| 9 |
|
Deportivo Merlo | 7 | 2 | 2 | 3 | 3:4 | -1 | 8 |
| 10 |
|
Talleres (RdE) | 7 | 2 | 2 | 3 | 8:11 | -3 | 8 |
| 11 |
|
UAI Urquiza | 7 | 2 | 2 | 3 | 6:9 | -3 | 8 |
| 12 |
|
Argentino de Quilmes | 6 | 1 | 4 | 1 | 5:5 | 0 | 7 |
| 13 |
|
Dock Sud | 6 | 2 | 1 | 3 | 5:7 | -2 | 7 |
| 14 |
|
Acassuso | 6 | 1 | 3 | 2 | 5:6 | -1 | 6 |
| 15 |
|
Justo José de Urquiza | 6 | 1 | 3 | 2 | 6:8 | -2 | 6 |
| 16 |
|
Atlético San Miguel | 6 | 1 | 1 | 4 | 4:9 | -5 | 4 |
| 17 |
|
CA Los Andes | 7 | 0 | 4 | 3 | 5:11 | -6 | 4 |
| Play-offs |
