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| 28.04.2018 | 00:00 | Chacarita Juniors | - | Temperley | 1:2 (0:2) | |
| 02:15 | Godoy Cruz | - | San Martín de San Juan | 2:0 (1:0) | ||
| 18:15 | Defensa y Justicia | - | Rosario Central | 3:1 (1:0) | ||
| 18:15 | Vélez Sarsfield | - | Banfield | 1:0 (0:0) | ||
| 20:30 | Newell's Old Boys | - | Independiente | 0:1 (0:1) | ||
| 22:45 | Lanús | - | Argentinos Juniors | 0:0 (0:0) | ||
| 29.04.2018 | 01:00 | Huracán | - | Atlético Tucumán | 3:2 (1:0) | |
| 18:15 | Patronato de Paraná | - | San Lorenzo | 0:0 (0:0) | ||
| 20:30 | Belgrano de Córdoba | - | Colón de Santa Fe | 1:0 (1:0) | ||
| 01.05.2018 | 00:00 | Unión de Santa Fe | - | Talleres de Córdoba | 3:0 (0:0) | |
| 02:15 | Olimpo de Bahía Blanca | - | Tigre | 1:5 (0:3) | ||
| 09.05.2018 | 22:00 | Racing Club | - | Arsenal de Sarandí | 2:0 (0:0) | |
| 10.05.2018 | 00:15 | Gimnasia de La Plata | - | Boca Juniors | 2:2 (1:1) | |
| 11.05.2018 | 21:45 | River Plate | - | Estudiantes | 2:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors | 25 | 17 | 3 | 5 | 45:19 | 26 | 54 |
| 2 |
|
Godoy Cruz | 25 | 15 | 5 | 5 | 41:23 | 18 | 50 |
| 3 |
|
San Lorenzo | 25 | 13 | 8 | 4 | 29:18 | 11 | 47 |
| 4 |
|
Huracán | 25 | 13 | 7 | 5 | 32:21 | 11 | 46 |
| 5 |
|
Independiente | 25 | 13 | 6 | 6 | 27:16 | 11 | 45 |
| 6 |
|
Talleres de Córdoba | 25 | 13 | 5 | 7 | 31:18 | 13 | 44 |
| 7 |
|
Racing Club | 25 | 12 | 6 | 7 | 43:28 | 15 | 42 |
| 8 |
|
River Plate | 25 | 12 | 5 | 8 | 37:26 | 11 | 41 |
| 9 |
|
Defensa y Justicia | 25 | 12 | 5 | 8 | 39:33 | 6 | 41 |
| 10 |
|
Unión de Santa Fe | 25 | 10 | 10 | 5 | 32:21 | 11 | 40 |
| 11 |
|
Argentinos Juniors | 25 | 12 | 4 | 9 | 34:27 | 7 | 40 |
| 12 |
|
Belgrano de Córdoba | 25 | 10 | 10 | 5 | 27:23 | 4 | 40 |
| 13 |
|
Colón de Santa Fe | 25 | 10 | 7 | 8 | 29:21 | 8 | 37 |
| 14 |
|
Estudiantes | 25 | 10 | 5 | 10 | 23:23 | 0 | 35 |
| 15 |
|
Atlético Tucumán | 25 | 8 | 10 | 7 | 28:25 | 3 | 34 |
| 16 |
|
Vélez Sarsfield | 25 | 9 | 7 | 9 | 28:31 | -3 | 34 |
| 17 |
|
Banfield | 25 | 8 | 7 | 10 | 25:23 | 2 | 31 |
| 18 |
|
Rosario Central | 25 | 8 | 7 | 10 | 29:36 | -7 | 31 |
| 19 |
|
San Martín de San Juan | 25 | 8 | 6 | 11 | 26:33 | -7 | 30 |
| 20 |
|
Patronato de Paraná | 25 | 7 | 8 | 10 | 24:31 | -7 | 29 |
| 21 |
|
Lanús | 25 | 6 | 9 | 10 | 20:37 | -17 | 27 |
| 22 |
|
Newell's Old Boys | 25 | 7 | 6 | 12 | 22:26 | -4 | 24 |
| 23 |
|
Tigre | 25 | 4 | 11 | 10 | 26:31 | -5 | 23 |
| 24 |
|
Gimnasia de La Plata | 25 | 6 | 5 | 14 | 24:41 | -17 | 23 |
| 25 |
|
Temperley | 25 | 4 | 8 | 13 | 18:42 | -24 | 20 |
| 26 |
|
Chacarita Juniors | 25 | 4 | 6 | 15 | 21:34 | -13 | 18 |
| 27 |
|
Arsenal de Sarandí | 25 | 2 | 8 | 15 | 15:34 | -19 | 14 |
| 28 |
|
Olimpo de Bahía Blanca | 25 | 3 | 4 | 18 | 13:47 | -34 | 13 |
| Copa Libertadores | |
| Copa Sudamericana |
