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| 12.03.2021 | 23:15 | Aldosivi | - | Central Córdoba SdE | 1:2 (1:2) | |
| 13.03.2021 | 01:30 | Unión de Santa Fe | - | Gimnasia de La Plata | 1:1 (1:0) | |
| 01:30 | Huracán | - | Lanús | 0:0 (0:0) | ||
| 21:10 | Platense | - | Racing Club | 0:2 (0:0) | ||
| 21:10 | Talleres de Córdoba | - | Vélez Sarsfield | 0:1 (0:0) | ||
| 23:20 | Argentinos Juniors | - | Godoy Cruz | 2:0 (1:0) | ||
| 23:20 | Defensa y Justicia | - | Newell's Old Boys | 4:0 (2:0) | ||
| 14.03.2021 | 01:30 | Estudiantes | - | Colón de Santa Fe | 0:2 (0:1) | |
| 22:00 | Boca Juniors | - | River Plate | 1:1 (1:0) | ||
| 15.03.2021 | 01:30 | Banfield | - | San Lorenzo | 0:0 (0:0) | |
| 23:15 | Rosario Central | - | Arsenal de Sarandí | 2:1 (1:0) | ||
| 23:15 | Atlético Tucumán | - | Patronato de Paraná | 4:2 (2:1) | ||
| 16.03.2021 | 01:30 | Independiente | - | Sarmiento de Junín | 6:0 (4:0) |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colón de Santa Fe | 5 | 5 | 0 | 0 | 12:1 | 11 | 15 |
| 2 |
|
Estudiantes | 5 | 3 | 1 | 1 | 9:3 | 6 | 10 |
| 3 |
|
Central Córdoba SdE | 5 | 3 | 1 | 1 | 9:6 | 3 | 10 |
| 4 |
|
Banfield | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
|
Racing Club | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 | |
| 6 |
|
River Plate | 5 | 2 | 1 | 2 | 6:4 | 2 | 7 |
| 7 |
|
Godoy Cruz | 5 | 2 | 1 | 2 | 7:8 | -1 | 7 |
| 8 |
|
Rosario Central | 5 | 2 | 1 | 2 | 6:8 | -2 | 7 |
| 9 |
|
Argentinos Juniors | 5 | 2 | 0 | 3 | 4:5 | -1 | 6 |
| 10 |
|
San Lorenzo | 5 | 1 | 2 | 2 | 3:8 | -5 | 5 |
| 11 |
|
Aldosivi | 5 | 1 | 1 | 3 | 8:8 | 0 | 4 |
| 12 |
|
Platense | 5 | 1 | 1 | 3 | 3:7 | -4 | 4 |
| 13 |
|
Arsenal de Sarandí | 5 | 0 | 0 | 5 | 2:14 | -12 | 0 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Independiente | 5 | 4 | 0 | 1 | 10:2 | 8 | 12 |
| 2 |
|
Vélez Sarsfield | 5 | 4 | 0 | 1 | 7:8 | -1 | 12 |
| 3 |
|
Defensa y Justicia | 5 | 3 | 1 | 1 | 10:5 | 5 | 10 |
| 4 |
|
Lanús | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 |
| 5 |
|
Boca Juniors | 5 | 2 | 3 | 0 | 12:5 | 7 | 9 |
| 6 |
|
Unión de Santa Fe | 5 | 2 | 3 | 0 | 8:6 | 2 | 9 |
| 7 |
|
Gimnasia de La Plata | 5 | 1 | 3 | 1 | 7:5 | 2 | 6 |
| 8 |
|
Atlético Tucumán | 5 | 1 | 2 | 2 | 9:9 | 0 | 5 |
| 9 |
|
Talleres de Córdoba | 5 | 1 | 2 | 2 | 4:7 | -3 | 5 |
| 10 |
|
Huracán | 5 | 0 | 4 | 1 | 5:6 | -1 | 4 |
| 11 |
|
Sarmiento de Junín | 5 | 0 | 3 | 2 | 4:11 | -7 | 3 |
| 12 |
|
Newell's Old Boys | 5 | 0 | 1 | 4 | 3:10 | -7 | 1 |
| 13 |
|
Patronato de Paraná | 5 | 0 | 0 | 5 | 2:8 | -6 | 0 |
| Play-offs | |
| Play-offs |
