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| 26.03.2021 | 23:00 | Lanús | - | Patronato de Paraná | 4:2 (1:0) | |
| 27.03.2021 | 01:15 | Unión de Santa Fe | - | Sarmiento de Junín | 0:0 (0:0) | |
| 18:00 | Platense | - | Colón de Santa Fe | 1:3 (0:0) | ||
| 20:15 | Aldosivi | - | Banfield | 1:1 (0:0) | ||
| 22:30 | Argentinos Juniors | - | Arsenal de Sarandí | 3:2 (0:1) | ||
| 28.03.2021 | 01:00 | Rosario Central | - | Central Córdoba SdE | 2:2 (1:0) | |
| 19:00 | Talleres de Córdoba | - | Godoy Cruz | 1:1 (0:1) | ||
| 21:15 | Defensa y Justicia | - | Vélez Sarsfield | 1:1 (1:0) | ||
| 23:30 | River Plate | - | Racing Club | 0:0 (0:0) | ||
| 29.03.2021 | 02:00 | Independiente | - | Boca Juniors | 1:1 (1:0) | |
| 30.03.2021 | 00:00 | Estudiantes | - | San Lorenzo | 0:2 (0:1) | |
| 02:15 | Atlético Tucumán | - | Newell's Old Boys | 2:2 (0:1) | ||
| 02:15 | Huracán | - | Gimnasia de La Plata | 1:1 (1:0) |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Colón de Santa Fe | 7 | 6 | 1 | 0 | 15:2 | 13 | 19 |
| 2 |
|
Central Córdoba SdE | 7 | 3 | 3 | 1 | 12:9 | 3 | 12 |
| 3 |
|
Banfield | 7 | 3 | 3 | 1 | 8:5 | 3 | 12 |
| 4 |
|
Racing Club | 7 | 3 | 3 | 1 | 6:4 | 2 | 12 |
| 5 |
|
River Plate | 7 | 3 | 2 | 2 | 12:5 | 7 | 11 |
| 6 |
|
Estudiantes | 7 | 3 | 2 | 2 | 10:6 | 4 | 11 |
| 7 |
|
Argentinos Juniors | 7 | 3 | 0 | 4 | 7:8 | -1 | 9 |
| 8 |
|
Rosario Central | 7 | 2 | 3 | 2 | 8:10 | -2 | 9 |
| 9 |
|
Aldosivi | 7 | 2 | 2 | 3 | 11:10 | 1 | 8 |
| 10 |
|
San Lorenzo | 7 | 2 | 2 | 3 | 6:10 | -4 | 8 |
| 11 |
|
Godoy Cruz | 7 | 2 | 2 | 3 | 9:15 | -6 | 8 |
| 12 |
|
Platense | 7 | 1 | 2 | 4 | 4:10 | -6 | 5 |
| 13 |
|
Arsenal de Sarandí | 7 | 0 | 1 | 6 | 4:17 | -13 | 1 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Vélez Sarsfield | 7 | 5 | 1 | 1 | 9:9 | 0 | 16 |
| 2 |
|
Independiente | 7 | 4 | 1 | 2 | 11:4 | 7 | 13 |
| 3 |
|
Lanús | 7 | 4 | 1 | 2 | 11:9 | 2 | 13 |
| 4 |
|
Defensa y Justicia | 7 | 3 | 2 | 2 | 12:9 | 3 | 11 |
| 5 |
|
Unión de Santa Fe | 7 | 2 | 5 | 0 | 8:6 | 2 | 11 |
| 6 |
|
Boca Juniors | 7 | 2 | 4 | 1 | 14:8 | 6 | 10 |
| 7 |
|
Gimnasia de La Plata | 7 | 2 | 4 | 1 | 10:6 | 4 | 10 |
| 8 |
|
Talleres de Córdoba | 7 | 2 | 3 | 2 | 7:9 | -2 | 9 |
| 9 |
|
Huracán | 7 | 1 | 5 | 1 | 7:7 | 0 | 8 |
| 10 |
|
Sarmiento de Junín | 7 | 1 | 4 | 2 | 7:12 | -5 | 7 |
| 11 |
|
Atlético Tucumán | 7 | 1 | 3 | 3 | 11:13 | -2 | 6 |
| 12 |
|
Newell's Old Boys | 7 | 0 | 3 | 4 | 5:12 | -7 | 3 |
| 13 |
|
Patronato de Paraná | 7 | 0 | 0 | 7 | 4:13 | -9 | 0 |
| Play-offs | |
| Play-offs |
