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| 25.06.2022 | 00:00 | Banfield | - | Barracas Central | 1:1 (0:1) | |
| 00:00 | Rosario Central | - | Gimnasia de La Plata | 0:1 (0:0) | ||
| 02:30 | Boca Juniors | - | Unión de Santa Fe | 1:2 (1:1) | ||
| 20:30 | Defensa y Justicia | - | Vélez Sarsfield | 1:1 (0:0) | ||
| 20:30 | Talleres de Córdoba | - | Central Córdoba SdE | 0:2 (0:0) | ||
| 23:00 | Colón de Santa Fe | - | Huracán | 0:1 (0:1) | ||
| 23:00 | Estudiantes | - | Newell's Old Boys | 0:2 (0:0) | ||
| 26.06.2022 | 01:30 | River Plate | - | Lanús | 2:1 (2:1) | |
| 18:00 | San Lorenzo | - | Tigre | 1:1 (0:1) | ||
| 20:30 | Platense | - | Sarmiento de Junín | 0:0 (0:0) | ||
| 23:00 | Racing Club | - | Aldosivi | 5:0 (2:0) | ||
| 27.06.2022 | 01:30 | Argentinos Juniors | - | Arsenal de Sarandí | 1:1 (1:0) | |
| 20:30 | Patronato de Paraná | - | Independiente | 3:1 (2:1) | ||
| 28.06.2022 | 01:00 | Atlético Tucumán | - | Godoy Cruz | 1:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Newell's Old Boys | 5 | 4 | 1 | 0 | 6:1 | 5 | 13 |
| 2 |
|
Gimnasia de La Plata | 5 | 3 | 2 | 0 | 8:3 | 5 | 11 |
| 3 |
|
Racing Club | 5 | 3 | 0 | 2 | 10:5 | 5 | 9 |
| 4 |
|
Boca Juniors | 5 | 3 | 0 | 2 | 11:8 | 3 | 9 |
| 5 |
|
Platense | 5 | 2 | 3 | 0 | 4:2 | 2 | 9 |
| 6 |
|
River Plate | 5 | 2 | 2 | 1 | 7:3 | 4 | 8 |
| 7 |
|
Banfield | 5 | 2 | 2 | 1 | 5:4 | 1 | 8 |
| 8 |
|
Huracán | 5 | 2 | 2 | 1 | 4:3 | 1 | 8 |
| 9 |
|
San Lorenzo | 5 | 1 | 4 | 0 | 7:5 | 2 | 7 |
| 10 |
|
Godoy Cruz | 5 | 2 | 1 | 2 | 6:5 | 1 | 7 |
| 11 |
|
Atlético Tucumán | 5 | 1 | 4 | 0 | 4:3 | 1 | 7 |
| 12 |
|
Argentinos Juniors | 5 | 2 | 1 | 2 | 5:5 | 0 | 7 |
|
Central Córdoba SdE | 5 | 2 | 1 | 2 | 5:5 | 0 | 7 | |
|
Sarmiento de Junín | 5 | 2 | 1 | 2 | 5:5 | 0 | 7 | |
| 15 |
|
Independiente | 5 | 2 | 1 | 2 | 6:7 | -1 | 7 |
|
Patronato de Paraná | 5 | 2 | 1 | 2 | 6:7 | -1 | 7 | |
| 17 |
|
Estudiantes | 5 | 2 | 1 | 2 | 5:6 | -1 | 7 |
| 18 |
|
Unión de Santa Fe | 5 | 2 | 1 | 2 | 8:11 | -3 | 7 |
| 19 |
|
Colón de Santa Fe | 5 | 1 | 2 | 2 | 4:5 | -1 | 5 |
|
Lanús | 5 | 1 | 2 | 2 | 4:5 | -1 | 5 | |
|
Vélez Sarsfield | 5 | 1 | 2 | 2 | 4:5 | -1 | 5 | |
| 22 |
|
Tigre | 5 | 1 | 2 | 2 | 7:9 | -2 | 5 |
| 23 |
|
Arsenal de Sarandí | 5 | 0 | 4 | 1 | 6:7 | -1 | 4 |
| 24 |
|
Defensa y Justicia | 5 | 0 | 4 | 1 | 4:5 | -1 | 4 |
| 25 |
|
Talleres de Córdoba | 5 | 1 | 1 | 3 | 3:5 | -2 | 4 |
| 26 |
|
Rosario Central | 5 | 1 | 1 | 3 | 1:5 | -4 | 4 |
| 27 |
|
Barracas Central | 5 | 0 | 3 | 2 | 5:8 | -3 | 3 |
| 28 |
|
Aldosivi | 5 | 0 | 1 | 4 | 1:9 | -8 | 1 |
