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| 07.10.2022 | 15:00 | Defensa y Justicia II | - | Rosario Central II | 0:6 (0:4) | |
| 16:00 | Arsenal de Sarandí II | - | Unión de Santa Fe II | 0:0 (0:0) | ||
| 16:00 | Godoy Cruz II | - | Talleres de Córdoba II | 2:4 (2:2) | ||
| 08.10.2022 | 15:00 | River Plate II | - | Patronato de Paraná II | 2:0 (0:0) | |
| 15:00 | Colón de Santa Fe II | - | Platense II | 0:1 (0:0) | ||
| 15:00 | Atlético Tucumán II | - | Racing Club II | 0:1 (0:1) | ||
| 09.10.2022 | 15:00 | Sarmiento de Junín II | - | Barracas Central II | 1:0 (0:0) | |
| 16:00 | Newell's Old Boys II | - | Central Córdoba SdE II | 0:0 (0:0) | ||
| 10.10.2022 | 15:00 | Vélez Sarsfield II | - | San Lorenzo II | 2:0 (1:0) | |
| 15:00 | Huracán II | - | Argentinos Juniors II | 1:2 (0:0) | ||
| 16:00 | Lanús II | - | Estudiantes II | 1:0 (1:0) | ||
| 16:00 | Independiente II | - | Tigre II | 1:1 (1:1) | ||
| 16:00 | Aldosivi II | - | Boca Juniors II | 0:2 (0:1) | ||
| 16:00 | Gimnasia de La Plata II | - | Banfield II | 1:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors II | 24 | 15 | 3 | 6 | 41:19 | 22 | 48 |
| 2 |
|
Vélez Sarsfield II | 24 | 15 | 2 | 7 | 42:17 | 25 | 47 |
| 3 |
|
Newell's Old Boys II | 24 | 11 | 8 | 5 | 32:23 | 9 | 41 |
| 4 |
|
Tigre II | 24 | 11 | 8 | 5 | 30:24 | 6 | 41 |
| 5 |
|
Lanús II | 24 | 12 | 4 | 8 | 39:37 | 2 | 40 |
| 6 |
|
River Plate II | 24 | 13 | 1 | 10 | 26:24 | 2 | 40 |
| 7 |
|
Gimnasia de La Plata II | 24 | 11 | 6 | 7 | 43:29 | 14 | 39 |
| 8 |
|
Huracán II | 24 | 12 | 3 | 9 | 47:37 | 10 | 39 |
| 9 |
|
Independiente II | 24 | 11 | 6 | 7 | 38:28 | 10 | 39 |
| 10 |
|
Argentinos Juniors II | 24 | 10 | 9 | 5 | 33:23 | 10 | 39 |
| 11 |
|
Talleres de Córdoba II | 24 | 11 | 4 | 9 | 39:32 | 7 | 37 |
| 12 |
|
Defensa y Justicia II | 24 | 10 | 5 | 9 | 26:30 | -4 | 35 |
| 13 |
|
Rosario Central II | 24 | 9 | 7 | 8 | 41:32 | 9 | 34 |
| 14 |
|
Unión de Santa Fe II | 24 | 8 | 9 | 7 | 21:21 | 0 | 33 |
| 15 |
|
Platense II | 24 | 7 | 11 | 6 | 24:22 | 2 | 32 |
| 16 |
|
Colón de Santa Fe II | 24 | 8 | 8 | 8 | 32:33 | -1 | 32 |
| 17 |
|
Godoy Cruz II | 24 | 8 | 7 | 9 | 32:32 | 0 | 31 |
| 18 |
|
Estudiantes II | 24 | 7 | 9 | 8 | 21:24 | -3 | 30 |
| 19 |
|
San Lorenzo II | 24 | 9 | 3 | 12 | 27:31 | -4 | 30 |
| 20 |
|
Banfield II | 24 | 8 | 6 | 10 | 23:27 | -4 | 30 |
| 21 |
|
Arsenal de Sarandí II | 24 | 6 | 10 | 8 | 23:24 | -1 | 28 |
| 22 |
|
Sarmiento de Junín II | 24 | 8 | 4 | 12 | 20:35 | -15 | 28 |
| 23 |
|
Racing Club II | 24 | 6 | 8 | 10 | 30:29 | 1 | 26 |
| 24 |
|
Central Córdoba SdE II | 24 | 7 | 5 | 12 | 21:35 | -14 | 26 |
| 25 |
|
Atlético Tucumán II | 24 | 6 | 5 | 13 | 28:39 | -11 | 23 |
| 26 |
|
Patronato de Paraná II | 24 | 5 | 5 | 14 | 18:39 | -21 | 20 |
| 27 |
|
Barracas Central II | 24 | 6 | 2 | 16 | 17:46 | -29 | 20 |
| 28 |
|
Aldosivi II | 24 | 5 | 4 | 15 | 28:50 | -22 | 19 |
