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| 05.08.2022 | 20:45 | Sarmiento de Resistencia | - | Juventud Antoniana | 2:1 (1:0) | |
| 06.08.2022 | 02:30 | Central Norte | - | Atlético Paraná | 0:1 (0:1) | |
| 20:00 | San Martín de Formosa | - | Gimnasia y Tiro de Salta | 4:0 (2:0) | ||
| 07.08.2022 | 16:00 | Defensores de Pronunciamiento | - | Unión de Sunchales | 1:1 (0:1) | |
| 20:00 | Belgrano de San Francisco | - | Boca Unidos | 2:1 (1:1) | ||
| 20:15 | Douglas Haig | - | Crucero del Norte | 2:0 (0:0) | ||
| 20:30 | Defensores Belgrano (VR) | - | Sportivo Las Parejas | 0:0 (0:0) | ||
| 21:00 | Racing de Córdoba | - | Juventud Unida de Gualeguaychú | 4:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Racing de Córdoba | 22 | 13 | 8 | 1 | 40:12 | 28 | 47 |
| 2 |
|
Sarmiento de Resistencia | 22 | 12 | 8 | 2 | 31:11 | 20 | 44 |
| 3 |
|
San Martín de Formosa | 21 | 11 | 5 | 5 | 38:21 | 17 | 38 |
| 4 |
|
Central Norte | 21 | 10 | 8 | 3 | 30:17 | 13 | 38 |
| 5 |
|
Douglas Haig | 22 | 10 | 5 | 7 | 33:20 | 13 | 35 |
| 6 |
|
Gimnasia y Esgrima (CdU) | 21 | 10 | 5 | 6 | 25:19 | 6 | 35 |
| 7 |
|
Sportivo Las Parejas | 22 | 9 | 7 | 6 | 24:19 | 5 | 34 |
| 8 |
|
Gimnasia y Tiro de Salta | 22 | 10 | 4 | 8 | 21:25 | -4 | 34 |
| 9 |
|
Belgrano de San Francisco | 22 | 9 | 4 | 9 | 29:26 | 3 | 31 |
| 10 |
|
Crucero del Norte | 22 | 7 | 6 | 9 | 17:28 | -11 | 27 |
| 11 |
|
Juventud Antoniana | 22 | 7 | 5 | 10 | 19:27 | -8 | 26 |
| 12 |
|
Defensores Belgrano (VR) | 22 | 6 | 4 | 12 | 18:25 | -7 | 22 |
| 13 |
|
Boca Unidos | 21 | 4 | 9 | 8 | 17:22 | -5 | 21 |
| 14 |
|
Atlético Paraná | 22 | 4 | 7 | 11 | 18:32 | -14 | 19 |
| 15 |
|
Unión de Sunchales | 22 | 5 | 4 | 13 | 22:37 | -15 | 19 |
| 16 |
|
Defensores de Pronunciamiento | 21 | 3 | 8 | 10 | 13:30 | -17 | 17 |
| 17 |
|
Juventud Unida de Gualeguaychú | 21 | 4 | 3 | 14 | 17:41 | -24 | 15 |
| Play-offs |
