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| 03.04.2021 | 16:15 | KV Oostende | - | Waasland-Beveren | 0:2 (0:2) | |
| 18:30 | Sint-Truidense VV | - | KV Mechelen | 2:1 (2:0) | ||
| 20:45 | KV Kortrijk | - | Club Brugge KV | 1:2 (1:1) | ||
| 04.04.2021 | 13:30 | Cercle Brugge | - | K Beerschot VA | 2:1 (2:0) | |
| 18:15 | Standard Luik | - | KAA Gent | 2:1 (0:1) | ||
| 20:45 | Sporting Charleroi | - | Royal Excel Mouscron | 1:1 (0:0) | ||
| 05.04.2021 | 13:30 | Oud-Heverlee Leuven | - | KRC Genk | 2:3 (0:1) | |
| 16:00 | SV Zulte Waregem | - | KAS Eupen | 2:1 (0:1) | ||
| 18:15 | Royal Antwerp FC | - | RSC Anderlecht | 1:4 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Brugge KV | 32 | 23 | 4 | 5 | 68:22 | 46 | 73 |
| 2 |
|
Royal Antwerp FC | 32 | 16 | 6 | 10 | 51:44 | 7 | 54 |
| 3 |
|
KRC Genk | 32 | 15 | 8 | 9 | 61:45 | 16 | 53 |
| 4 |
|
RSC Anderlecht | 32 | 13 | 13 | 6 | 48:33 | 15 | 52 |
| 5 |
|
KV Oostende | 32 | 14 | 7 | 11 | 46:39 | 7 | 49 |
| 6 |
|
K Beerschot VA | 32 | 14 | 5 | 13 | 57:59 | -2 | 47 |
| 7 |
|
SV Zulte Waregem | 32 | 14 | 4 | 14 | 49:58 | -9 | 46 |
| 8 |
|
Oud-Heverlee Leuven | 32 | 12 | 9 | 11 | 53:54 | -1 | 45 |
| 9 |
|
Standard Luik | 32 | 11 | 11 | 10 | 45:41 | 4 | 44 |
| 10 |
|
KAA Gent | 32 | 12 | 7 | 13 | 44:40 | 4 | 43 |
| 11 |
|
Sporting Charleroi | 32 | 11 | 9 | 12 | 44:42 | 2 | 42 |
| 12 |
|
KV Mechelen | 32 | 11 | 9 | 12 | 46:51 | -5 | 42 |
| 13 |
|
KAS Eupen | 32 | 9 | 13 | 10 | 41:49 | -8 | 40 |
| 14 |
|
Sint-Truidense VV | 32 | 10 | 8 | 14 | 41:47 | -6 | 38 |
| 15 |
|
KV Kortrijk | 32 | 10 | 6 | 16 | 39:50 | -11 | 36 |
| 16 |
|
Cercle Brugge | 32 | 10 | 2 | 20 | 36:50 | -14 | 32 |
| 17 |
|
Royal Excel Mouscron | 32 | 7 | 10 | 15 | 28:47 | -19 | 31 |
| 18 |
|
Waasland-Beveren | 32 | 7 | 7 | 18 | 39:65 | -26 | 28 |
| Play-offs | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
