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| 05.09.2022 | 19:00 | Lommel SK II | - | Excelsior Virton II | 2:2 | |
| 19:30 | KAS Eupen II | - | Lierse Kempenzonen II | 2:1 | ||
| 19:30 | KV Kortrijk II | - | SK Beveren II | 0:3 | ||
| 20:00 | FCV Dender EH II | - | KV Oostende II | 2:2 | ||
| 20:00 | SK Deinze II | - | Sint-Truidense VV II | 0:4 | ||
| 20:00 | KVC Westerlo II | - | RWDM Brussels FC II | 3:2 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sint-Truidense VV II | 3 | 3 | 0 | 0 | 9:0 | 9 | 9 |
| 2 |
|
KVC Westerlo II | 3 | 3 | 0 | 0 | 9:4 | 5 | 9 |
| 3 |
|
KV Oostende II | 3 | 2 | 1 | 0 | 11:3 | 8 | 7 |
| 4 |
|
SK Beveren II | 3 | 2 | 1 | 0 | 6:2 | 4 | 7 |
| 5 |
|
KAS Eupen II | 3 | 2 | 1 | 0 | 7:4 | 3 | 7 |
| 6 |
|
FCV Dender EH II | 3 | 1 | 1 | 1 | 8:7 | 1 | 4 |
| 7 |
|
RWDM Brussels FC II | 3 | 1 | 1 | 1 | 6:6 | 0 | 4 |
| 8 |
|
Excelsior Virton II | 3 | 0 | 1 | 2 | 7:11 | -4 | 1 |
| 9 |
|
KV Kortrijk II | 3 | 0 | 1 | 2 | 3:8 | -5 | 1 |
| 10 |
|
Lommel SK II | 3 | 0 | 1 | 2 | 3:11 | -8 | 1 |
| 11 |
|
Lierse Kempenzonen II | 3 | 0 | 0 | 3 | 1:7 | -6 | 0 |
| 12 |
|
SK Deinze II | 3 | 0 | 0 | 3 | 2:9 | -7 | 0 |
