 |
 |
|
| 23.04.2022 | 13:30 | SV Zulte Waregem | - | Standard Liège | 0:2 | |
| 14:00 | Sint-Truidense VV | - | RSC Anderlecht | 1:1 | ||
| 14:00 | Sporting Charleroi | - | Royal Antwerp FC | 2:1 | ||
| 14:00 | Cercle Brugge | - | KAA Gent | 1:2 | ||
| 14:30 | KV Mechelen | - | Oud-Heverlee Leuven | 1:3 | ||
| 07.05.2022 | 14:00 | Club Brugge KV | - | KVC Westerlo | 5:2 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RSC Anderlecht | 24 | 20 | 4 | 0 | 72:17 | 55 | 64 |
| 2 |
|
KRC Genk | 24 | 17 | 3 | 4 | 71:37 | 34 | 54 |
| 3 |
|
Standard Liège | 24 | 13 | 4 | 7 | 43:37 | 6 | 43 |
| 4 |
|
Sporting Charleroi | 24 | 11 | 8 | 5 | 50:40 | 10 | 41 |
| 5 |
|
Club Brugge KV | 24 | 12 | 4 | 8 | 54:37 | 17 | 40 |
| 6 |
|
KAA Gent | 24 | 10 | 4 | 10 | 42:48 | -6 | 34 |
| 7 |
|
Sint-Truidense VV | 24 | 8 | 9 | 7 | 39:38 | 1 | 33 |
| 8 |
|
Oud-Heverlee Leuven | 24 | 9 | 3 | 12 | 47:43 | 4 | 30 |
| 9 |
|
Royal Antwerp FC | 24 | 5 | 8 | 11 | 38:45 | -7 | 23 |
| 10 |
|
KV Mechelen | 24 | 5 | 6 | 13 | 32:53 | -21 | 21 |
| 11 |
|
SV Zulte Waregem | 24 | 3 | 9 | 12 | 27:47 | -20 | 18 |
| 12 |
|
Cercle Brugge | 24 | 5 | 2 | 17 | 34:74 | -40 | 17 |
| 13 |
|
KVC Westerlo | 24 | 3 | 6 | 15 | 33:66 | -33 | 15 |
