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| 29.12.2021 | 20:45 | Blackburn Rovers | - | Barnsley FC | 2:1 (1:1) | |
| 20:45 | Blackpool FC | - | Middlesbrough FC | 1:2 (0:0) | ||
| 20:45 | Coventry City | - | Millwall FC | 0:1 (0:0) | ||
| 30.12.2021 | 20:45 | AFC Bournemouth | - | Cardiff City | 3:0 (1:0) | |
| 20:45 | Bristol City | - | Queens Park Rangers | 1:2 (1:1) | ||
| 20:45 | Nottingham Forest | - | Huddersfield Town | 0:1 (0:1) | ||
| 20:45 | Stoke City | - | Derby County | 1:2 (0:1) | ||
| 11.01.2022 | 21:00 | Reading FC | - | Fulham FC | 0:7 (0:2) | |
| 25.01.2022 | 20:45 | Birmingham City | - | Peterborough United | 2:2 (0:1) | |
| 26.01.2022 | 21:00 | West Bromwich Albion | - | Preston North End | 0:2 (0:1) | |
| 01.02.2022 | 20:45 | Swansea City | - | Luton Town | 0:1 (0:0) | |
| 15.02.2022 | 20:45 | Sheffield United | - | Hull City | 0:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fulham FC | 25 | 15 | 6 | 4 | 64:21 | 43 | 51 |
| 2 |
|
AFC Bournemouth | 25 | 14 | 7 | 4 | 41:20 | 21 | 49 |
| 3 |
|
Blackburn Rovers | 25 | 13 | 6 | 6 | 43:30 | 13 | 45 |
| 4 |
|
West Bromwich Albion | 25 | 11 | 8 | 6 | 30:20 | 10 | 41 |
| 5 |
|
Queens Park Rangers | 25 | 11 | 6 | 8 | 35:30 | 5 | 39 |
| 6 |
|
Middlesbrough FC | 25 | 11 | 6 | 8 | 29:24 | 5 | 39 |
| 7 |
|
Huddersfield Town | 25 | 11 | 6 | 8 | 32:29 | 3 | 39 |
| 8 |
|
Luton Town | 25 | 10 | 8 | 7 | 36:28 | 8 | 38 |
| 9 |
|
Sheffield United | 25 | 10 | 7 | 8 | 32:30 | 2 | 37 |
| 10 |
|
Coventry City | 25 | 10 | 7 | 8 | 30:29 | 1 | 37 |
| 11 |
|
Stoke City | 25 | 10 | 6 | 9 | 28:25 | 3 | 36 |
| 12 |
|
Nottingham Forest | 25 | 9 | 7 | 9 | 32:28 | 4 | 34 |
| 13 |
|
Millwall FC | 25 | 8 | 10 | 7 | 25:25 | 0 | 34 |
| 14 |
|
Preston North End | 25 | 8 | 9 | 8 | 28:30 | -2 | 33 |
| 15 |
|
Swansea City | 25 | 8 | 7 | 10 | 27:32 | -5 | 31 |
| 16 |
|
Blackpool FC | 25 | 8 | 6 | 11 | 26:32 | -6 | 30 |
| 17 |
|
Birmingham City | 25 | 7 | 7 | 11 | 26:38 | -12 | 28 |
| 18 |
|
Cardiff City | 25 | 8 | 4 | 13 | 28:42 | -14 | 28 |
| 19 |
|
Hull City | 25 | 7 | 6 | 12 | 22:28 | -6 | 27 |
| 20 |
|
Bristol City | 25 | 7 | 6 | 12 | 28:39 | -11 | 27 |
| 21 |
|
Reading FC | 25 | 8 | 4 | 13 | 27:43 | -16 | 22 |
| 22 |
|
Peterborough United | 25 | 5 | 6 | 14 | 22:46 | -24 | 21 |
| 23 |
|
Barnsley FC | 25 | 2 | 9 | 14 | 17:37 | -20 | 15 |
| 24 |
|
Derby County | 25 | 7 | 10 | 8 | 21:23 | -2 | 10 |
| Promotie | |
| Play-offs | |
| Degradatie |
