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| 19.02.2022 | 13:30 | Fulham FC | - | Huddersfield Town | 1:2 (0:2) | |
| 16:00 | Bristol City | - | Middlesbrough FC | 2:1 (1:0) | ||
| 16:00 | Cardiff City | - | Blackpool FC | 1:1 (0:1) | ||
| 16:00 | Coventry City | - | Barnsley FC | 1:0 (0:0) | ||
| 16:00 | Derby County | - | Peterborough United | 1:0 (0:0) | ||
| 16:00 | Luton Town | - | West Bromwich Albion | 2:0 (0:0) | ||
| 16:00 | Preston North End | - | Reading FC | 2:3 (0:2) | ||
| 16:00 | Queens Park Rangers | - | Hull City | 1:1 (0:1) | ||
| 16:00 | Sheffield United | - | Swansea City | 4:0 (3:0) | ||
| 16:00 | Stoke City | - | Birmingham City | 2:2 (1:1) | ||
| 08.03.2022 | 20:45 | Blackburn Rovers | - | Millwall FC | 0:0 (0:0) | |
| 03.05.2022 | 20:00 | AFC Bournemouth | - | Nottingham Forest | 1:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fulham FC | 33 | 21 | 7 | 5 | 85:29 | 56 | 70 |
| 2 |
|
AFC Bournemouth | 33 | 18 | 8 | 7 | 51:29 | 22 | 62 |
| 3 |
|
Sheffield United | 33 | 16 | 8 | 9 | 48:34 | 14 | 56 |
| 4 |
|
Blackburn Rovers | 33 | 15 | 10 | 8 | 45:33 | 12 | 55 |
| 5 |
|
Queens Park Rangers | 33 | 15 | 8 | 10 | 47:38 | 9 | 53 |
| 6 |
|
Huddersfield Town | 33 | 14 | 11 | 8 | 42:35 | 7 | 53 |
| 7 |
|
Luton Town | 33 | 14 | 10 | 9 | 45:37 | 8 | 52 |
| 8 |
|
Nottingham Forest | 33 | 14 | 8 | 11 | 45:34 | 11 | 50 |
| 9 |
|
West Bromwich Albion | 33 | 13 | 10 | 10 | 36:28 | 8 | 49 |
| 10 |
|
Middlesbrough FC | 33 | 14 | 7 | 12 | 40:36 | 4 | 49 |
| 11 |
|
Coventry City | 33 | 13 | 8 | 12 | 40:39 | 1 | 47 |
| 12 |
|
Stoke City | 33 | 12 | 9 | 12 | 42:37 | 5 | 45 |
| 13 |
|
Blackpool FC | 33 | 12 | 9 | 12 | 37:38 | -1 | 45 |
|
Preston North End | 33 | 11 | 12 | 10 | 37:38 | -1 | 45 | |
| 15 |
|
Millwall FC | 33 | 11 | 11 | 11 | 33:34 | -1 | 44 |
| 16 |
|
Swansea City | 33 | 11 | 8 | 14 | 34:48 | -14 | 41 |
| 17 |
|
Bristol City | 33 | 11 | 7 | 15 | 44:59 | -15 | 40 |
| 18 |
|
Cardiff City | 33 | 11 | 6 | 16 | 40:51 | -11 | 39 |
| 19 |
|
Birmingham City | 33 | 9 | 10 | 14 | 39:51 | -12 | 37 |
| 20 |
|
Hull City | 33 | 9 | 7 | 17 | 27:37 | -10 | 34 |
| 21 |
|
Reading FC | 33 | 10 | 5 | 18 | 41:63 | -22 | 29 |
| 22 |
|
Peterborough United | 33 | 5 | 8 | 20 | 25:63 | -38 | 23 |
| 23 |
|
Derby County | 33 | 10 | 12 | 11 | 33:36 | -3 | 21 |
| 24 |
|
Barnsley FC | 33 | 3 | 9 | 21 | 20:49 | -29 | 18 |
| Promotie | |
| Play-offs | |
| Degradatie |
