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| 19.03.2022 | 13:30 | Derby County | - | Coventry City | 1:1 (0:1) | |
| 13:30 | Sheffield United | - | Barnsley FC | 2:0 (0:0) | ||
| 16:00 | Bristol City | - | West Bromwich Albion | 2:2 (1:0) | ||
| 16:00 | Reading FC | - | Blackburn Rovers | 1:0 (0:0) | ||
| 16:00 | Huddersfield Town | - | AFC Bournemouth | 0:3 (0:2) | ||
| 16:00 | Hull City | - | Luton Town | 1:3 (0:1) | ||
| 16:00 | Stoke City | - | Millwall FC | 2:0 (1:0) | ||
| 16:00 | Swansea City | - | Birmingham City | 0:0 (0:0) | ||
| 20.03.2022 | 13:30 | Queens Park Rangers | - | Peterborough United | 1:3 (1:1) | |
| 05.04.2022 | 20:45 | Preston North End | - | Blackpool FC | 1:0 (1:0) | |
| 26.04.2022 | 20:45 | Fulham FC | - | Nottingham Forest | 0:1 (0:1) | |
| 27.04.2022 | 20:45 | Middlesbrough FC | - | Cardiff City | 2:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Fulham FC | 39 | 24 | 8 | 7 | 91:33 | 58 | 80 |
| 2 |
|
AFC Bournemouth | 39 | 21 | 10 | 8 | 63:36 | 27 | 73 |
| 3 |
|
Nottingham Forest | 39 | 18 | 10 | 11 | 56:36 | 20 | 64 |
| 4 |
|
Luton Town | 39 | 18 | 10 | 11 | 57:43 | 14 | 64 |
| 5 |
|
Sheffield United | 39 | 18 | 10 | 11 | 53:40 | 13 | 64 |
| 6 |
|
Huddersfield Town | 39 | 17 | 12 | 10 | 51:43 | 8 | 63 |
| 7 |
|
Middlesbrough FC | 39 | 18 | 8 | 13 | 50:41 | 9 | 62 |
| 8 |
|
Blackburn Rovers | 39 | 17 | 10 | 12 | 49:39 | 10 | 61 |
| 9 |
|
Queens Park Rangers | 39 | 17 | 8 | 14 | 54:49 | 5 | 59 |
| 10 |
|
West Bromwich Albion | 39 | 15 | 12 | 12 | 44:36 | 8 | 57 |
| 11 |
|
Millwall FC | 39 | 15 | 12 | 12 | 39:37 | 2 | 57 |
| 12 |
|
Blackpool FC | 39 | 15 | 10 | 14 | 44:42 | 2 | 55 |
| 13 |
|
Coventry City | 39 | 15 | 10 | 14 | 49:48 | 1 | 55 |
| 14 |
|
Preston North End | 39 | 13 | 15 | 11 | 41:44 | -3 | 54 |
| 15 |
|
Swansea City | 39 | 14 | 10 | 15 | 45:55 | -10 | 52 |
| 16 |
|
Stoke City | 39 | 13 | 10 | 16 | 49:46 | 3 | 49 |
| 17 |
|
Cardiff City | 39 | 13 | 7 | 19 | 45:58 | -13 | 46 |
| 18 |
|
Bristol City | 39 | 12 | 8 | 19 | 49:69 | -20 | 44 |
| 19 |
|
Birmingham City | 39 | 10 | 12 | 17 | 42:58 | -16 | 42 |
| 20 |
|
Hull City | 39 | 11 | 8 | 20 | 33:44 | -11 | 41 |
| 21 |
|
Reading FC | 39 | 12 | 6 | 21 | 46:74 | -28 | 36 |
| 22 |
|
Barnsley FC | 39 | 6 | 10 | 23 | 28:56 | -28 | 28 |
| 23 |
|
Peterborough United | 39 | 6 | 9 | 24 | 33:77 | -44 | 27 |
| 24 |
|
Derby County | 39 | 11 | 13 | 15 | 38:45 | -7 | 25 |
| Promotie | |
| Play-offs | |
| Degradatie |
