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| 24.04.2021 | 14:00 | Elche CF | - | Levante UD | 1:0 (1:0) | |
| 16:15 | Real Valladolid | - | Cádiz CF | 1:1 (1:0) | ||
| 18:30 | Valencia CF | - | Deportivo Alavés | 1:1 (0:0) | ||
| 21:00 | Real Madrid | - | Real Betis | 0:0 (0:0) | ||
| 25.04.2021 | 14:00 | SD Huesca | - | Getafe CF | 0:2 (0:1) | |
| 16:15 | Villarreal CF | - | FC Barcelona | 1:2 (1:2) | ||
| 18:30 | Celta de Vigo | - | CA Osasuna | 2:1 (1:0) | ||
| 18:30 | Sevilla FC | - | Granada CF | 2:1 (1:0) | ||
| 21:00 | Athletic Bilbao | - | Atlético Madrid | 2:1 (1:0) | ||
| 26.04.2021 | 21:00 | SD Eibar | - | Real Sociedad | 0:1 (0:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Barcelona | 32 | 22 | 5 | 5 | 76:29 | 47 | 71 |
| 2 |
|
Atlético Madrid | 32 | 21 | 7 | 4 | 55:22 | 33 | 70 |
| 3 |
|
Real Madrid | 32 | 21 | 7 | 4 | 56:24 | 32 | 70 |
| 4 |
|
Sevilla FC | 32 | 21 | 4 | 7 | 47:25 | 22 | 67 |
| 5 |
|
Real Sociedad | 32 | 14 | 11 | 7 | 50:32 | 18 | 53 |
| 6 |
|
Real Betis | 32 | 14 | 7 | 11 | 40:43 | -3 | 49 |
| 7 |
|
Villarreal CF | 32 | 11 | 13 | 8 | 45:37 | 8 | 46 |
| 8 |
|
Granada CF | 32 | 12 | 6 | 14 | 41:53 | -12 | 42 |
| 9 |
|
Athletic Bilbao | 32 | 10 | 11 | 11 | 41:34 | 7 | 41 |
| 10 |
|
Celta de Vigo | 32 | 10 | 10 | 12 | 44:51 | -7 | 40 |
| 11 |
|
Levante UD | 32 | 9 | 11 | 12 | 37:41 | -4 | 38 |
| 12 |
|
CA Osasuna | 32 | 9 | 10 | 13 | 29:39 | -10 | 37 |
| 13 |
|
Cádiz CF | 32 | 9 | 9 | 14 | 28:49 | -21 | 36 |
| 14 |
|
Valencia CF | 32 | 8 | 11 | 13 | 39:46 | -7 | 35 |
| 15 |
|
Getafe CF | 32 | 8 | 9 | 15 | 26:39 | -13 | 33 |
| 16 |
|
Elche CF | 32 | 6 | 12 | 14 | 29:47 | -18 | 30 |
| 17 |
|
Real Valladolid | 32 | 5 | 14 | 13 | 29:43 | -14 | 29 |
| 18 |
|
Deportivo Alavés | 32 | 6 | 10 | 16 | 27:49 | -22 | 28 |
| 19 |
|
SD Huesca | 32 | 5 | 12 | 15 | 31:49 | -18 | 27 |
| 20 |
|
SD Eibar | 32 | 4 | 11 | 17 | 23:41 | -18 | 23 |
| Champions League | |
| Europa League | |
| Europa League Kwali. | |
| Degradatie |
