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| 30.04.2021 | 21:00 | Celta de Vigo | - | Levante UD | 2:0 (0:0) | |
| 01.05.2021 | 14:00 | SD Eibar | - | Deportivo Alavés | 3:0 (1:0) | |
| 16:15 | Elche CF | - | Atlético Madrid | 0:1 (0:1) | ||
| 18:30 | SD Huesca | - | Real Sociedad | 1:0 (0:0) | ||
| 21:00 | Real Madrid | - | CA Osasuna | 2:0 (0:0) | ||
| 02.05.2021 | 14:00 | Real Valladolid | - | Real Betis | 1:1 (0:0) | |
| 16:15 | Villarreal CF | - | Getafe CF | 1:0 (0:0) | ||
| 18:30 | Granada CF | - | Cádiz CF | 0:1 (0:1) | ||
| 21:00 | Valencia CF | - | FC Barcelona | 2:3 (0:0) | ||
| 03.05.2021 | 21:00 | Sevilla FC | - | Athletic Bilbao | 0:1 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Madrid | 34 | 23 | 7 | 4 | 61:22 | 39 | 76 |
| 2 |
|
FC Barcelona | 34 | 23 | 5 | 6 | 80:33 | 47 | 74 |
| 3 |
|
Real Madrid | 34 | 22 | 8 | 4 | 58:24 | 34 | 74 |
| 4 |
|
Sevilla FC | 34 | 22 | 4 | 8 | 49:27 | 22 | 70 |
| 5 |
|
Real Sociedad | 34 | 14 | 11 | 9 | 51:35 | 16 | 53 |
| 6 |
|
Villarreal CF | 34 | 13 | 13 | 8 | 51:38 | 13 | 52 |
| 7 |
|
Real Betis | 34 | 14 | 9 | 11 | 43:46 | -3 | 51 |
| 8 |
|
Granada CF | 34 | 13 | 6 | 15 | 43:55 | -12 | 45 |
| 9 |
|
Athletic Bilbao | 34 | 11 | 12 | 11 | 44:36 | 8 | 45 |
| 10 |
|
Celta de Vigo | 34 | 11 | 11 | 12 | 46:51 | -5 | 44 |
| 11 |
|
CA Osasuna | 34 | 10 | 10 | 14 | 31:41 | -10 | 40 |
| 12 |
|
Cádiz CF | 34 | 10 | 10 | 14 | 29:49 | -20 | 40 |
| 13 |
|
Levante UD | 34 | 9 | 11 | 14 | 38:48 | -10 | 38 |
| 14 |
|
Valencia CF | 34 | 8 | 12 | 14 | 43:51 | -8 | 36 |
| 15 |
|
Getafe CF | 34 | 8 | 10 | 16 | 26:40 | -14 | 34 |
| 16 |
|
Real Valladolid | 34 | 5 | 16 | 13 | 32:46 | -14 | 31 |
| 17 |
|
Deportivo Alavés | 34 | 7 | 10 | 17 | 28:52 | -24 | 31 |
| 18 |
|
SD Huesca | 34 | 6 | 12 | 16 | 32:50 | -18 | 30 |
| 19 |
|
Elche CF | 34 | 6 | 12 | 16 | 29:50 | -21 | 30 |
| 20 |
|
SD Eibar | 34 | 5 | 11 | 18 | 26:46 | -20 | 26 |
| Champions League | |
| Europa League | |
| Europa League Kwali. | |
| Degradatie |
