 |
 |
|
| 20.05.2022 | 21:00 | Rayo Vallecano | - | Levante UD | 2:4 (1:3) | |
| 21:00 | Real Madrid | - | Real Betis | 0:0 (0:0) | ||
| 21.05.2022 | 17:30 | Valencia CF | - | Celta de Vigo | 2:0 (1:0) | |
| 22.05.2022 | 17:30 | Elche CF | - | Getafe CF | 3:1 (1:1) | |
| 20:00 | CA Osasuna | - | RCD Mallorca | 0:2 (0:0) | ||
| 20:00 | Deportivo Alavés | - | Cádiz CF | 0:1 (0:0) | ||
| 20:00 | Granada CF | - | Espanyol | 0:0 (0:0) | ||
| 22:00 | FC Barcelona | - | Villarreal CF | 0:2 (0:1) | ||
| 22:00 | Sevilla FC | - | Athletic Bilbao | 1:0 (0:0) | ||
| 22:00 | Real Sociedad | - | Atlético Madrid | 1:2 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Madrid | 38 | 26 | 8 | 4 | 80:31 | 49 | 86 |
| 2 |
|
FC Barcelona | 38 | 21 | 10 | 7 | 68:38 | 30 | 73 |
| 3 |
|
Atlético Madrid | 38 | 21 | 8 | 9 | 65:43 | 22 | 71 |
| 4 |
|
Sevilla FC | 38 | 18 | 16 | 4 | 53:30 | 23 | 70 |
| 5 |
|
Real Betis | 38 | 19 | 8 | 11 | 62:40 | 22 | 65 |
| 6 |
|
Real Sociedad | 38 | 17 | 11 | 10 | 40:37 | 3 | 62 |
| 7 |
|
Villarreal CF | 38 | 16 | 11 | 11 | 63:37 | 26 | 59 |
| 8 |
|
Athletic Bilbao | 38 | 14 | 13 | 11 | 43:36 | 7 | 55 |
| 9 |
|
Valencia CF | 38 | 11 | 15 | 12 | 48:53 | -5 | 48 |
| 10 |
|
CA Osasuna | 38 | 12 | 11 | 15 | 37:51 | -14 | 47 |
| 11 |
|
Celta de Vigo | 38 | 12 | 10 | 16 | 43:43 | 0 | 46 |
| 12 |
|
Rayo Vallecano | 38 | 11 | 9 | 18 | 39:50 | -11 | 42 |
| 13 |
|
Elche CF | 38 | 11 | 9 | 18 | 40:52 | -12 | 42 |
| 14 |
|
Espanyol | 38 | 10 | 12 | 16 | 40:53 | -13 | 42 |
| 15 |
|
Getafe CF | 38 | 8 | 15 | 15 | 33:41 | -8 | 39 |
| 16 |
|
RCD Mallorca | 38 | 10 | 9 | 19 | 36:63 | -27 | 39 |
| 17 |
|
Cádiz CF | 38 | 8 | 15 | 15 | 35:51 | -16 | 39 |
| 18 |
|
Granada CF | 38 | 8 | 14 | 16 | 44:61 | -17 | 38 |
| 19 |
|
Levante UD | 38 | 8 | 11 | 19 | 51:76 | -25 | 35 |
| 20 |
|
Deportivo Alavés | 38 | 8 | 7 | 23 | 31:65 | -34 | 31 |
| Champions League | |
| Europa League | |
| Degradatie |
