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| 21.04.2018 | 17:00 | Real Betis B | - | FC Cartagena | 1:2 (0:1) | |
| 17:30 | Lorca Deportiva | - | FC Jumilla | 1:2 (0:0) | ||
| 18:00 | UCAM Murcia CF | - | Mérida AD | 1:1 (0:0) | ||
| 18:00 | CD El Ejido 2012 | - | Marbella FC | 1:1 (0:1) | ||
| 18:00 | Écija Balompié | - | Granada CF B | 3:1 (0:1) | ||
| 22.04.2018 | 12:00 | RB Linense | - | UD Las Palmas B | 1:3 (0:1) | |
| 17:00 | Extremadura UD | - | CF Villanovense | 0:1 (0:1) | ||
| 18:00 | Recreativo Huelva | - | San Fernando CD | 2:1 (0:0) | ||
| 18:00 | CD Badajoz | - | Real Murcia | 2:3 (1:1) | ||
| 25.04.2018 | 20:00 | UD Melilla | - | Córdoba CF B | 3:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Cartagena | 35 | 19 | 9 | 7 | 49:33 | 16 | 66 |
| 2 |
|
Marbella FC | 35 | 18 | 10 | 7 | 46:25 | 21 | 64 |
| 3 |
|
Real Murcia | 35 | 17 | 11 | 7 | 47:30 | 17 | 62 |
| 4 |
|
Extremadura UD | 35 | 15 | 9 | 11 | 52:37 | 15 | 54 |
| 5 |
|
UD Melilla | 35 | 15 | 9 | 11 | 39:23 | 16 | 54 |
| 6 |
|
CF Villanovense | 35 | 13 | 12 | 10 | 28:31 | -3 | 51 |
| 7 |
|
CD El Ejido 2012 | 35 | 12 | 12 | 11 | 51:48 | 3 | 48 |
| 8 |
|
Granada CF B | 35 | 12 | 12 | 11 | 32:32 | 0 | 48 |
| 9 |
|
UCAM Murcia CF | 35 | 12 | 12 | 11 | 35:39 | -4 | 48 |
| 10 |
|
San Fernando CD | 35 | 11 | 12 | 12 | 42:41 | 1 | 45 |
| 11 |
|
RB Linense | 35 | 10 | 14 | 11 | 42:36 | 6 | 44 |
| 12 |
|
Écija Balompié | 35 | 11 | 11 | 13 | 37:51 | -14 | 44 |
| 13 |
|
Mérida AD | 35 | 10 | 13 | 12 | 32:38 | -6 | 43 |
| 14 |
|
Recreativo Huelva | 35 | 11 | 10 | 14 | 31:34 | -3 | 43 |
| 15 |
|
CD Badajoz | 35 | 10 | 12 | 13 | 43:41 | 2 | 42 |
| 16 |
|
UD Las Palmas B | 35 | 11 | 9 | 15 | 40:41 | -1 | 42 |
| 17 |
|
FC Jumilla | 35 | 8 | 14 | 13 | 26:42 | -16 | 38 |
| 18 |
|
Córdoba CF B | 35 | 9 | 10 | 16 | 37:49 | -12 | 37 |
| 19 |
|
Real Betis B | 35 | 7 | 13 | 15 | 43:55 | -12 | 34 |
| 20 |
|
Lorca Deportiva | 35 | 8 | 8 | 19 | 33:59 | -26 | 32 |
| Play-offs | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
