 |
 |
|
|
| U | Fenerbahçe | - | Zenit St. Petersburg | 1:0 (1:0) | ||
| R | Zenit St. Petersburg | - | Fenerbahçe | 3:1 (2:1) | ||
| U: 12.02.2019 18:55 | R: 21.02.2019 18:55 | Winnaars: Zenit St. Petersburg | ||||
| U | Rapid Wien | - | Inter | 0:1 (0:1) | ||
| R | Inter | - | Rapid Wien | 4:0 (2:0) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: Inter | ||||
| U | Slavia Praag | - | KRC Genk | 0:0 (0:0) | ||
| R | KRC Genk | - | Slavia Praag | 1:4 (1:1) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: Slavia Praag | ||||
| U | FK Krasnodar | - | Bayer Leverkusen | 0:0 (0:0) | ||
| R | Bayer Leverkusen | - | FK Krasnodar | 1:1 (0:0) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: FK Krasnodar | ||||
| U | Stade Rennais | - | Real Betis | 3:3 (3:1) | ||
| R | Real Betis | - | Stade Rennais | 1:3 (1:2) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: Stade Rennais | ||||
| U | Olympiakos | - | Dinamo Kiev | 2:2 (2:1) | ||
| R | Dinamo Kiev | - | Olympiakos | 1:0 (1:0) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: Dinamo Kiev | ||||
| U | Lazio Roma | - | Sevilla FC | 0:1 (0:1) | ||
| R | Sevilla FC | - | Lazio Roma | 2:0 (1:0) | ||
| U: 14.02.2019 18:55 | R: 20.02.2019 18:00 | Winnaars: Sevilla FC | ||||
| U | BATE Borisov | - | Arsenal FC | 1:0 (1:0) | ||
| R | Arsenal FC | - | BATE Borisov | 3:0 (2:0) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 18:55 | Winnaars: Arsenal FC | ||||
| U | Galatasaray | - | SL Benfica | 1:2 (0:1) | ||
| R | SL Benfica | - | Galatasaray | 0:0 (0:0) | ||
| U: 14.02.2019 18:55 | R: 21.02.2019 21:00 | Winnaars: SL Benfica | ||||
| U | Viktoria Plzeň | - | Dinamo Zagreb | 2:1 (0:1) | ||
| R | Dinamo Zagreb | - | Viktoria Plzeň | 3:0 (2:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: Dinamo Zagreb | ||||
| U | Club Brugge KV | - | RB Salzburg | 2:1 (0:1) | ||
| R | RB Salzburg | - | Club Brugge KV | 4:0 (3:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: RB Salzburg | ||||
| U | FC Zürich | - | SSC Napoli | 1:3 (0:2) | ||
| R | SSC Napoli | - | FC Zürich | 2:0 (1:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: SSC Napoli | ||||
| U | Malmö FF | - | Chelsea FC | 1:2 (0:1) | ||
| R | Chelsea FC | - | Malmö FF | 3:0 (0:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 21:00 | Winnaars: Chelsea FC | ||||
| U | Shakhtar Donetsk | - | Eintracht Frankfurt | 2:2 (1:1) | ||
| R | Eintracht Frankfurt | - | Shakhtar Donetsk | 4:1 (2:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: Eintracht Frankfurt | ||||
| U | Celtic FC | - | Valencia CF | 0:2 (0:1) | ||
| R | Valencia CF | - | Celtic FC | 1:0 (0:0) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: Valencia CF | ||||
| U | Sporting CP | - | Villarreal CF | 0:1 (0:1) | ||
| R | Villarreal CF | - | Sporting CP | 1:1 (0:1) | ||
| U: 14.02.2019 21:00 | R: 21.02.2019 18:55 | Winnaars: Villarreal CF | ||||
