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| U | AZ Alkmaar | - | Tottenham Hotspur | 1:0 (1:0) | ||
| R | Tottenham Hotspur | - | AZ Alkmaar | 3:1 (1:0) | ||
| U: 06.03.2025 18:45 | R: 13.03.2025 21:00 | Winnaars: Tottenham Hotspur | ||||
| U | Real Sociedad | - | Manchester United | 1:1 (0:0) | ||
| R | Manchester United | - | Real Sociedad | 4:1 (1:1) | ||
| U: 06.03.2025 18:45 | R: 13.03.2025 21:00 | Winnaars: Manchester United | ||||
| U | FCSB | - | Olympique Lyonnais | 1:3 (0:1) | ||
| R | Olympique Lyonnais | - | FCSB | 4:0 (2:0) | ||
| U: 06.03.2025 18:45 | R: 13.03.2025 21:00 | Winnaars: Olympique Lyonnais | ||||
| U | Fenerbahçe | - | Rangers FC | 1:3 (1:2) | ||
| R | Rangers FC | - | Fenerbahçe | 3:2 (0:1, 0:2, 0:2) d.p. | ||
| U: 06.03.2025 18:45 | R: 13.03.2025 21:00 | Winnaars: Rangers FC | ||||
| U | AS Roma | - | Athletic Club | 2:1 (0:0) | ||
| R | Athletic Club | - | AS Roma | 3:1 (1:0) | ||
| U: 06.03.2025 21:00 | R: 13.03.2025 18:45 | Winnaars: Athletic Club | ||||
| U | FK Bodø/Glimt | - | Olympiakos | 3:0 (2:0) | ||
| R | Olympiakos | - | FK Bodø/Glimt | 2:1 (0:1) | ||
| U: 06.03.2025 21:00 | R: 13.03.2025 18:45 | Winnaars: FK Bodø/Glimt | ||||
| U | AFC Ajax | - | Eintracht Frankfurt | 1:2 (1:1) | ||
| R | Eintracht Frankfurt | - | AFC Ajax | 4:1 (2:0) | ||
| U: 06.03.2025 21:00 | R: 13.03.2025 18:45 | Winnaars: Eintracht Frankfurt | ||||
| U | Viktoria Plzeň | - | Lazio | 1:2 (0:1) | ||
| R | Lazio | - | Viktoria Plzeň | 1:1 (0:0) | ||
| U: 06.03.2025 21:00 | R: 13.03.2025 18:45 | Winnaars: Lazio | ||||
