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| 01.05.2022 | 15:00 | Havre AC | - | Évreux FC 27 | 2:0 (2:0) | |
| 15:00 | Paris Saint-Germain | - | SM Caen | 4:1 (3:0) | ||
| 15:00 | JA Drancy | - | FC Chambly | 1:1 (0:1) | ||
| 15:00 | Amiens SC | - | Valenciennes FC | 1:4 (1:1) | ||
| 15:00 | Entente Feignies Aulnoye | - | US Orléans | 1:1 (0:1) | ||
| 15:00 | Lille OSC | - | RC Lens | 2:0 (0:0) | ||
| 15:00 | St-Pryvé St-Hilaire | - | Montfermeil FC | 0:2 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 25 | 20 | 2 | 3 | 89:24 | 65 | 62 |
| 2 |
|
Valenciennes FC | 25 | 14 | 1 | 10 | 36:29 | 7 | 43 |
| 3 |
|
JA Drancy | 25 | 12 | 7 | 6 | 45:39 | 6 | 43 |
| 4 |
|
Amiens SC | 25 | 13 | 4 | 8 | 50:36 | 14 | 43 |
| 5 |
|
SM Caen | 25 | 13 | 3 | 9 | 46:45 | 1 | 42 |
| 6 |
|
Havre AC | 25 | 11 | 8 | 6 | 48:33 | 15 | 41 |
| 7 |
|
Montfermeil FC | 25 | 13 | 2 | 10 | 34:28 | 6 | 41 |
| 8 |
|
US Orléans | 25 | 11 | 6 | 8 | 48:33 | 15 | 39 |
| 9 |
|
Lille OSC | 25 | 9 | 6 | 10 | 43:41 | 2 | 33 |
| 10 |
|
RC Lens | 25 | 7 | 7 | 11 | 27:38 | -11 | 28 |
| 11 |
|
FC Chambly | 25 | 5 | 9 | 11 | 24:33 | -9 | 24 |
| 12 |
|
Entente Feignies Aulnoye | 25 | 7 | 3 | 15 | 30:41 | -11 | 24 |
| 13 |
|
Évreux FC 27 | 25 | 4 | 4 | 17 | 25:65 | -40 | 16 |
| 14 |
|
St-Pryvé St-Hilaire | 25 | 4 | 2 | 19 | 15:75 | -60 | 14 |
| Play-offs | |
| Degradatie |
