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| 07.01.2022 | 21:00 | Girondins Bordeaux | - | Olympique Marseille | 0:1 (0:1) | |
| 08.01.2022 | 21:00 | RC Lens | - | Stade Rennais | 1:0 (0:0) | |
| 09.01.2022 | 13:00 | Stade Brestois | - | OGC Nice | 0:3 (0:1) | |
| 15:00 | Clermont Foot 63 | - | Stade Reims | 0:0 (0:0) | ||
| 15:00 | FC Metz | - | RC Strasbourg | 0:2 (0:0) | ||
| 17:00 | FC Nantes | - | AS Monaco | 0:0 (0:0) | ||
| 20:45 | Olympique Lyon | - | Paris Saint-Germain | 1:1 (1:0) | ||
| 19.01.2022 | 19:00 | Montpellier HSC | - | ESTAC Troyes | 0:1 (0:0) | |
| 19:00 | Lille OSC | - | FC Lorient | 3:1 (3:0) | ||
| 26.01.2022 | 19:00 | Angers SCO | - | AS Saint-Étienne | 0:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 20 | 14 | 5 | 1 | 40:18 | 22 | 47 |
| 2 |
|
OGC Nice | 20 | 11 | 4 | 5 | 32:17 | 15 | 36 |
| 3 |
|
Olympique Marseille | 20 | 10 | 6 | 4 | 28:17 | 11 | 36 |
| 4 |
|
RC Strasbourg | 20 | 9 | 5 | 6 | 38:24 | 14 | 32 |
| 5 |
|
Stade Rennais | 20 | 9 | 4 | 7 | 34:19 | 15 | 31 |
| 6 |
|
Montpellier HSC | 20 | 9 | 4 | 7 | 33:25 | 8 | 31 |
| 7 |
|
Lille OSC | 20 | 8 | 7 | 5 | 29:27 | 2 | 31 |
| 8 |
|
RC Lens | 20 | 8 | 6 | 6 | 34:28 | 6 | 30 |
| 9 |
|
AS Monaco | 20 | 8 | 6 | 6 | 29:23 | 6 | 30 |
| 10 |
|
FC Nantes | 20 | 8 | 5 | 7 | 25:23 | 2 | 29 |
| 11 |
|
Olympique Lyon | 20 | 7 | 8 | 5 | 29:28 | 1 | 28 |
| 12 |
|
Angers SCO | 20 | 6 | 7 | 7 | 26:28 | -2 | 25 |
| 13 |
|
Stade Brestois | 20 | 6 | 7 | 7 | 26:31 | -5 | 25 |
| 14 |
|
Stade Reims | 20 | 5 | 9 | 6 | 22:22 | 0 | 24 |
| 15 |
|
ESTAC Troyes | 20 | 5 | 5 | 10 | 19:28 | -9 | 20 |
| 16 |
|
Clermont Foot 63 | 20 | 4 | 6 | 10 | 20:34 | -14 | 18 |
| 17 |
|
Girondins Bordeaux | 20 | 3 | 8 | 9 | 30:44 | -14 | 17 |
| 18 |
|
FC Metz | 20 | 3 | 7 | 10 | 23:41 | -18 | 16 |
| 19 |
|
FC Lorient | 20 | 3 | 7 | 10 | 16:34 | -18 | 16 |
| 20 |
|
AS Saint-Étienne | 20 | 3 | 6 | 11 | 18:40 | -22 | 15 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
