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| 21.01.2022 | 21:00 | Olympique Lyon | - | AS Saint-Étienne | 1:0 (1:0) | |
| 22.01.2022 | 17:00 | Stade Brestois | - | Lille OSC | 2:0 (1:0) | |
| 21:00 | RC Lens | - | Olympique Marseille | 0:2 (0:1) | ||
| 23.01.2022 | 13:00 | FC Metz | - | OGC Nice | 0:2 (0:0) | |
| 15:00 | Clermont Foot 63 | - | Stade Rennais | 2:1 (0:1) | ||
| 15:00 | FC Nantes | - | FC Lorient | 4:2 (1:0) | ||
| 15:00 | Girondins Bordeaux | - | RC Strasbourg | 4:3 (3:1) | ||
| 15:00 | Angers SCO | - | ESTAC Troyes | 2:1 (2:1) | ||
| 17:05 | Montpellier HSC | - | AS Monaco | 3:2 (2:1) | ||
| 20:45 | Paris Saint-Germain | - | Stade Reims | 4:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Paris Saint-Germain | 22 | 16 | 5 | 1 | 46:18 | 28 | 53 |
| 2 |
|
OGC Nice | 22 | 13 | 4 | 5 | 36:18 | 18 | 42 |
| 3 |
|
Olympique Marseille | 22 | 11 | 7 | 4 | 31:18 | 13 | 40 |
| 4 |
|
RC Strasbourg | 22 | 10 | 5 | 7 | 44:29 | 15 | 35 |
| 5 |
|
Stade Rennais | 22 | 10 | 4 | 8 | 41:21 | 20 | 34 |
| 6 |
|
Montpellier HSC | 22 | 10 | 4 | 8 | 37:30 | 7 | 34 |
| 7 |
|
Olympique Lyon | 22 | 9 | 8 | 5 | 31:28 | 3 | 34 |
| 8 |
|
AS Monaco | 22 | 9 | 6 | 7 | 35:26 | 9 | 33 |
| 9 |
|
RC Lens | 22 | 9 | 6 | 7 | 36:31 | 5 | 33 |
| 10 |
|
FC Nantes | 22 | 9 | 5 | 8 | 30:27 | 3 | 32 |
| 11 |
|
Lille OSC | 22 | 8 | 8 | 6 | 30:30 | 0 | 32 |
| 12 |
|
Angers SCO | 22 | 7 | 8 | 7 | 28:29 | -1 | 29 |
| 13 |
|
Stade Brestois | 22 | 7 | 7 | 8 | 28:33 | -5 | 28 |
| 14 |
|
Stade Reims | 22 | 5 | 9 | 8 | 22:27 | -5 | 24 |
| 15 |
|
Clermont Foot 63 | 22 | 5 | 6 | 11 | 22:39 | -17 | 21 |
| 16 |
|
ESTAC Troyes | 22 | 5 | 5 | 12 | 20:31 | -11 | 20 |
| 17 |
|
Girondins Bordeaux | 22 | 4 | 8 | 10 | 34:53 | -19 | 20 |
| 18 |
|
FC Metz | 22 | 4 | 7 | 11 | 24:43 | -19 | 19 |
| 19 |
|
FC Lorient | 22 | 3 | 8 | 11 | 18:38 | -20 | 17 |
| 20 |
|
AS Saint-Étienne | 22 | 3 | 6 | 13 | 19:43 | -24 | 15 |
| Champions League | |
| Champions League Kwali. | |
| Europa League | |
| Promotie en degradatie | |
| Degradatie |
