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| 24.09.2021 | 21:00 | AS Nancy Lorraine | - | Amiens SC | 1:1 (0:1) | |
| 21:00 | Dijon FCO | - | Valenciennes FC | 0:1 (0:1) | ||
| 21:00 | Chamois Niortais | - | Paris FC | 4:1 (2:0) | ||
| 21:00 | Pau FC | - | USL Dunkerque | 1:2 (0:2) | ||
| 21:00 | FC Sochaux | - | AJ Auxerre | 0:0 (0:0) | ||
| 21:00 | Nîmes Olympique | - | Havre AC | 0:1 (0:0) | ||
| 21:00 | Rodez AF | - | Grenoble Foot 38 | 1:1 (0:1) | ||
| 21:00 | US Quevilly-Rouen | - | EA Guingamp | 2:2 (2:2) | ||
| 25.09.2021 | 15:00 | SC Bastia | - | AC Ajaccio | 2:0 (0:0) | |
| 27.09.2021 | 20:45 | Toulouse FC | - | SM Caen | 2:3 (2:3) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 10 | 7 | 2 | 1 | 22:9 | 13 | 23 |
| 2 |
|
FC Sochaux | 10 | 6 | 2 | 2 | 11:6 | 5 | 20 |
| 3 |
|
AJ Auxerre | 10 | 5 | 4 | 1 | 16:5 | 11 | 19 |
| 4 |
|
AC Ajaccio | 10 | 5 | 4 | 1 | 12:6 | 6 | 19 |
| 5 |
|
Havre AC | 10 | 4 | 5 | 1 | 9:5 | 4 | 17 |
| 6 |
|
Paris FC | 10 | 5 | 1 | 4 | 13:11 | 2 | 16 |
| 7 |
|
Pau FC | 10 | 4 | 3 | 3 | 12:9 | 3 | 15 |
| 8 |
|
Chamois Niortais | 10 | 4 | 3 | 3 | 10:9 | 1 | 15 |
| 9 |
|
SM Caen | 10 | 4 | 2 | 4 | 12:10 | 2 | 14 |
| 10 |
|
Nîmes Olympique | 10 | 3 | 4 | 3 | 12:10 | 2 | 13 |
| 11 |
|
Rodez AF | 10 | 3 | 4 | 3 | 10:12 | -2 | 13 |
| 12 |
|
US Quevilly-Rouen | 10 | 3 | 3 | 4 | 11:12 | -1 | 12 |
| 13 |
|
Valenciennes FC | 10 | 3 | 3 | 4 | 8:13 | -5 | 12 |
| 14 |
|
EA Guingamp | 10 | 2 | 5 | 3 | 8:11 | -3 | 11 |
| 15 |
|
Grenoble Foot 38 | 10 | 3 | 2 | 5 | 10:16 | -6 | 11 |
| 16 |
|
SC Bastia | 10 | 2 | 4 | 4 | 9:11 | -2 | 10 |
| 17 |
|
Dijon FCO | 10 | 3 | 1 | 6 | 11:16 | -5 | 10 |
| 18 |
|
Amiens SC | 10 | 1 | 5 | 4 | 11:15 | -4 | 8 |
| 19 |
|
USL Dunkerque | 10 | 1 | 3 | 6 | 7:15 | -8 | 6 |
| 20 |
|
AS Nancy Lorraine | 10 | 0 | 4 | 6 | 6:19 | -13 | 4 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
