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| 11.09.2021 | 15:00 | Paris FC | - | EA Guingamp | 0:1 (0:1) | |
| 19:00 | AC Ajaccio | - | FC Sochaux | 1:0 (0:0) | ||
| 19:00 | AJ Auxerre | - | Chamois Niortais | 4:0 (1:0) | ||
| 19:00 | Dijon FCO | - | SC Bastia | 2:1 (0:0) | ||
| 19:00 | Valenciennes FC | - | US Quevilly-Rouen | 1:2 (1:0) | ||
| 19:00 | Grenoble Foot 38 | - | Nîmes Olympique | 2:1 (0:1) | ||
| 19:00 | Amiens SC | - | Rodez AF | 0:1 (0:1) | ||
| 19:00 | SM Caen | - | Pau FC | 1:2 (1:1) | ||
| 19:00 | USL Dunkerque | - | AS Nancy Lorraine | 0:0 (0:0) | ||
| 13.09.2021 | 20:45 | Havre AC | - | Toulouse FC | 1:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 7 | 5 | 2 | 0 | 14:5 | 9 | 17 |
| 2 |
|
AC Ajaccio | 7 | 4 | 3 | 0 | 10:4 | 6 | 15 |
| 3 |
|
AJ Auxerre | 7 | 4 | 2 | 1 | 15:5 | 10 | 14 |
| 4 |
|
Paris FC | 7 | 4 | 1 | 2 | 10:5 | 5 | 13 |
| 5 |
|
Pau FC | 7 | 4 | 1 | 2 | 8:4 | 4 | 13 |
| 6 |
|
FC Sochaux | 7 | 4 | 1 | 2 | 7:5 | 2 | 13 |
| 7 |
|
Nîmes Olympique | 7 | 3 | 3 | 1 | 9:4 | 5 | 12 |
| 8 |
|
Rodez AF | 7 | 3 | 3 | 1 | 9:8 | 1 | 12 |
| 9 |
|
SM Caen | 7 | 3 | 1 | 3 | 8:6 | 2 | 10 |
| 10 |
|
Havre AC | 7 | 2 | 4 | 1 | 6:4 | 2 | 10 |
| 11 |
|
US Quevilly-Rouen | 7 | 3 | 1 | 3 | 9:9 | 0 | 10 |
| 12 |
|
EA Guingamp | 7 | 2 | 4 | 1 | 5:5 | 0 | 10 |
| 13 |
|
Chamois Niortais | 7 | 2 | 2 | 3 | 4:8 | -4 | 8 |
| 14 |
|
Grenoble Foot 38 | 7 | 2 | 1 | 4 | 4:10 | -6 | 7 |
| 15 |
|
SC Bastia | 7 | 1 | 3 | 3 | 5:8 | -3 | 6 |
| 16 |
|
Amiens SC | 7 | 1 | 2 | 4 | 5:9 | -4 | 5 |
| 17 |
|
Valenciennes FC | 7 | 1 | 2 | 4 | 4:11 | -7 | 5 |
| 18 |
|
Dijon FCO | 7 | 1 | 1 | 5 | 8:15 | -7 | 4 |
| 19 |
|
USL Dunkerque | 7 | 0 | 3 | 4 | 5:10 | -5 | 3 |
| 20 |
|
AS Nancy Lorraine | 7 | 0 | 2 | 5 | 3:13 | -10 | 2 |
| Promotie | |
| Play-offs | |
| Promotie en degradatie | |
| Degradatie |
