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| 19.11.2021 | 20:00 | Andrézieux-Bouthéon FC | - | AS Béziers | 2:1 (1:0) | |
| 20.11.2021 | 18:00 | Canet Roussillon | - | Angoulême CFC | 0:0 (0:0) | |
| 18:00 | Bergerac Foot | - | Angers SCO II | 2:1 (2:1) | ||
| 18:00 | FC Nantes (CFA) | - | Trélissac FC | 2:1 (1:0) | ||
| 18:00 | Montpellier HSC (CFA) | - | Bourges Foot 18 | 2:3 (0:2) | ||
| 18:00 | US Colomiers | - | Moulins Yzeure Foot | 0:1 (0:0) | ||
| 18:00 | Vendée Les Herbiers | - | Le Puy Foot 43 | 0:2 (0:1) | ||
| 18:00 | FC Chamalières | - | Stade Montois | 2:1 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bergerac Foot | 12 | 7 | 3 | 2 | 19:9 | 10 | 24 |
| 2 |
|
Angoulême CFC | 12 | 6 | 4 | 2 | 18:12 | 6 | 22 |
| 3 |
|
Moulins Yzeure Foot | 12 | 6 | 4 | 2 | 11:7 | 4 | 22 |
| 4 |
|
Le Puy Foot 43 | 12 | 6 | 3 | 3 | 15:8 | 7 | 21 |
| 5 |
|
FC Nantes (CFA) | 12 | 5 | 5 | 2 | 16:12 | 4 | 20 |
| 6 |
|
Andrézieux-Bouthéon FC | 12 | 6 | 1 | 5 | 16:12 | 4 | 19 |
| 7 |
|
Bourges Foot 18 | 12 | 5 | 3 | 4 | 15:10 | 5 | 18 |
| 8 |
|
Trélissac FC | 12 | 5 | 2 | 5 | 11:12 | -1 | 17 |
| 9 |
|
AS Béziers | 12 | 4 | 3 | 5 | 11:14 | -3 | 15 |
| 10 |
|
Vendée Les Herbiers | 12 | 3 | 5 | 4 | 13:16 | -3 | 14 |
| 11 |
|
FC Chamalières | 12 | 4 | 2 | 6 | 15:19 | -4 | 14 |
| 12 |
|
US Colomiers | 12 | 3 | 4 | 5 | 10:12 | -2 | 13 |
| 13 |
|
Angers SCO II | 12 | 3 | 3 | 6 | 11:15 | -4 | 12 |
| 14 |
|
Canet Roussillon | 12 | 6 | 4 | 2 | 13:11 | 2 | 11 |
| 15 |
|
Montpellier HSC (CFA) | 12 | 3 | 2 | 7 | 14:17 | -3 | 11 |
| 16 |
|
Stade Montois | 12 | 0 | 0 | 12 | 9:31 | -22 | 0 |
| Promotie | |
| Degradatie |
