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| 22.04.2022 | 19:00 | FC Bourg-Péronnas | - | Red Star FC | 0:2 (0:2) | |
| 19:00 | FC Sète | - | US Orléans | 1:0 (0:0) | ||
| 19:00 | LB Châteauroux | - | FC Annecy | 0:1 (0:0) | ||
| 19:00 | Le Mans FC | - | FC Bastia-Borgo | 0:1 (0:1) | ||
| 19:00 | Stade Briochin | - | US Concarneau | 1:3 (1:1) | ||
| 19:00 | US Avranches | - | SO Cholet | 0:2 (0:2) | ||
| 19:00 | US Créteil-Lusitanos | - | FC Villefranche Beaujolais | 0:2 (0:0) | ||
| 23.04.2022 | 17:30 | CS Sedan | - | FC Chambly | 1:0 (0:0) | |
| 25.04.2022 | 18:45 | Stade Lavallois | - | US Boulogne | 1:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Stade Lavallois | 31 | 19 | 6 | 6 | 43:26 | 17 | 63 |
| 2 |
|
FC Annecy | 31 | 17 | 9 | 5 | 50:27 | 23 | 60 |
| 3 |
|
FC Villefranche Beaujolais | 31 | 16 | 8 | 7 | 40:27 | 13 | 56 |
| 4 |
|
US Concarneau | 31 | 14 | 13 | 4 | 43:25 | 18 | 55 |
| 5 |
|
LB Châteauroux | 31 | 14 | 9 | 8 | 39:26 | 13 | 51 |
| 6 |
|
FC Bourg-Péronnas | 31 | 14 | 8 | 9 | 51:33 | 18 | 50 |
| 7 |
|
Stade Briochin | 31 | 12 | 9 | 10 | 39:31 | 8 | 45 |
| 8 |
|
Le Mans FC | 31 | 12 | 9 | 10 | 32:29 | 3 | 45 |
| 9 |
|
CS Sedan | 31 | 11 | 11 | 9 | 35:35 | 0 | 44 |
| 10 |
|
US Orléans | 31 | 11 | 10 | 10 | 34:32 | 2 | 43 |
| 11 |
|
Red Star FC | 31 | 12 | 5 | 14 | 48:46 | 2 | 40 |
| 12 |
|
SO Cholet | 31 | 10 | 7 | 14 | 44:57 | -13 | 37 |
| 13 |
|
US Avranches | 31 | 10 | 6 | 15 | 30:51 | -21 | 36 |
| 14 |
|
FC Sète | 31 | 9 | 7 | 15 | 33:37 | -4 | 34 |
| 15 |
|
FC Bastia-Borgo | 31 | 6 | 9 | 16 | 37:56 | -19 | 27 |
| 16 |
|
FC Chambly | 31 | 6 | 8 | 17 | 34:55 | -21 | 26 |
| 17 |
|
US Créteil-Lusitanos | 31 | 6 | 7 | 18 | 30:50 | -20 | 25 |
| 18 |
|
US Boulogne | 31 | 5 | 9 | 17 | 27:46 | -19 | 23 |
| Promotie | |
| Promotie en degradatie | |
| Degradatie |
