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| 29.08.2021 | 11:00 | RB Leipzig | - | 1899 Hoffenheim II | 2:0 (1:0) | |
| 11:00 | SV Henstedt-Ulzburg | - | Bayern München II | 3:1 (2:1) | ||
| 11:00 | FC Ingolstadt 04 | - | SV Meppen | 0:4 (0:2) | ||
| 11:00 | MSV Duisburg | - | VfL Wolfsburg II | 1:0 (0:0) | ||
| 14:00 | 1. FC Nürnberg | - | Eintracht Frankfurt II | 0:0 (0:0) | ||
| 14:00 | SV 07 Elversberg | - | SG 99 Andernach | 1:1 (1:1) | ||
| 14:00 | Borussia Bocholt | - | FSV Gütersloh 2009 | 1:2 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SV Meppen | 2 | 2 | 0 | 0 | 9:0 | 9 | 6 |
| 2 |
|
RB Leipzig | 2 | 2 | 0 | 0 | 4:1 | 3 | 6 |
| 3 |
|
MSV Duisburg | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 4 |
|
Eintracht Frankfurt II | 2 | 1 | 1 | 0 | 4:1 | 3 | 4 |
| 5 |
|
1. FC Nürnberg | 2 | 1 | 1 | 0 | 3:0 | 3 | 4 |
| 6 |
|
SG 99 Andernach | 2 | 1 | 1 | 0 | 4:2 | 2 | 4 |
| 7 |
|
1899 Hoffenheim II | 2 | 1 | 0 | 1 | 4:3 | 1 | 3 |
| 8 |
|
FSV Gütersloh 2009 | 2 | 1 | 0 | 1 | 3:3 | 0 | 3 |
| 9 |
|
SV Henstedt-Ulzburg | 2 | 1 | 0 | 1 | 4:5 | -1 | 3 |
| 10 |
|
SV 07 Elversberg | 2 | 0 | 1 | 1 | 1:6 | -5 | 1 |
| 11 |
|
VfL Wolfsburg II | 2 | 0 | 0 | 2 | 1:3 | -2 | 0 |
| 12 |
|
Borussia Bocholt | 2 | 0 | 0 | 2 | 2:5 | -3 | 0 |
| 13 |
|
Bayern München II | 2 | 0 | 0 | 2 | 1:6 | -5 | 0 |
| 14 |
|
FC Ingolstadt 04 | 2 | 0 | 0 | 2 | 1:8 | -7 | 0 |
| Promotie | |
| Degradatie |
