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| U | Apollon Paralimniou | - | Agios Nikolaos | 2:2 (1:1) | ||
| R | Agios Nikolaos | - | Apollon Paralimniou | 1:2 (1:1, 1:1) n.v. | ||
| U: 14.12.2022 13:00 | R: 11.01.2023 13:00 | Winnaars: Apollon Paralimniou | ||||
| U | Kalamata | - | PAOK Saloniki | 0:2 (0:1) | ||
| R | PAOK Saloniki | - | Kalamata | 2:0 (2:0) | ||
| U: 14.12.2022 14:00 | R: 10.01.2023 20:00 | Winnaars: PAOK Saloniki | ||||
| U | Lamia | - | GS Kallithea | 1:1 (0:0) | ||
| R | GS Kallithea | - | Lamia | 1:2 (1:2) | ||
| U: 14.12.2022 17:00 | R: 10.01.2023 15:30 | Winnaars: Lamia | ||||
| U | Panathinaikos | - | Volos NFC | 3:0 (1:0) | ||
| R | Volos NFC | - | Panathinaikos | 0:2 (0:1) | ||
| U: 15.12.2022 16:30 | R: 11.01.2023 15:30 | Winnaars: Panathinaikos | ||||
| U | Olympiakos | - | Atromitos | 4:1 (1:1) | ||
| R | Atromitos | - | Olympiakos | 2:2 (1:2) | ||
| U: 15.12.2022 18:30 | R: 11.01.2023 20:00 | Winnaars: Olympiakos | ||||
| U | AE Kifisias | - | AEK Athene | 0:2 (0:2) | ||
| R | AEK Athene | - | AE Kifisias | 3:0 (1:0) | ||
| U: 15.12.2022 20:30 | R: 11.01.2023 18:00 | Winnaars: AEK Athene | ||||
| U | Panserraikos | - | Apollon Pontou | 3:0 (1:0) | ||
| R | Apollon Pontou | - | Panserraikos | 0:1 (0:1) | ||
| U: 16.12.2022 13:00 | R: 12.01.2023 13:00 | Winnaars: Panserraikos | ||||
| U | Levadiakos | - | Aris Saloniki | 1:2 (1:0) | ||
| R | Aris Saloniki | - | Levadiakos | 1:0 (1:0) | ||
| U: 16.12.2022 15:00 | R: 11.01.2023 15:00 | Winnaars: Aris Saloniki | ||||
