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| 24.11.2021 | APS Zakynthos | - | Levadiakos | 0:3 Toeg. | ||
| 14:00 | AE Karaiskakis | - | Kalamata | 0:1 (0:0) | ||
| 14:00 | Ergotelis | - | AEK Athen II | 0:0 (0:0) | ||
| 14:00 | Asteras Vlachioti | - | AE Kifisias | 0:1 (0:0) | ||
| 14:00 | Diagoras FC | - | AO Episkopi | 1:0 (0:0) | ||
| 14:00 | PAE Chania | - | AS Rhodos | 2:2 (2:1) | ||
| 14:00 | OFI Ierapetra | - | Irodotos | 1:1 (0:0) | ||
| 14:00 | GS Kallithea | - | AO Egaleo | 1:0 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AEK Athen II | 4 | 3 | 1 | 0 | 5:1 | 4 | 10 |
| 2 |
|
AE Kifisias | 4 | 3 | 0 | 1 | 6:2 | 4 | 9 |
| 3 |
|
GS Kallithea | 3 | 3 | 0 | 0 | 5:1 | 4 | 9 |
| 4 |
|
Levadiakos | 4 | 2 | 2 | 0 | 7:3 | 4 | 8 |
| 5 |
|
AO Egaleo | 4 | 2 | 1 | 1 | 4:2 | 2 | 7 |
| 6 |
|
Ergotelis | 4 | 2 | 1 | 1 | 3:2 | 1 | 7 |
| 7 |
|
Diagoras FC | 4 | 2 | 1 | 1 | 4:5 | -1 | 7 |
| 8 |
|
Irodotos | 4 | 1 | 2 | 1 | 4:3 | 1 | 5 |
| 9 |
|
PAE Chania | 4 | 0 | 4 | 0 | 4:4 | 0 | 4 |
| 10 |
|
Asteras Vlachioti | 4 | 1 | 1 | 2 | 2:3 | -1 | 4 |
| 11 |
|
AE Karaiskakis | 4 | 1 | 0 | 3 | 2:5 | -3 | 3 |
|
Panathinaikos II | 3 | 1 | 0 | 2 | 2:5 | -3 | 3 | |
| 13 |
|
OFI Ierapetra | 3 | 0 | 1 | 2 | 2:5 | -3 | 1 |
| 14 |
|
Kalamata | 3 | 1 | 0 | 2 | 2:3 | -1 | 0 |
| 15 |
|
AO Episkopi | 4 | 0 | 0 | 4 | 0:4 | -4 | 0 |
| 16 |
|
AS Rhodos | 4 | 2 | 2 | 0 | 6:2 | 4 | -7 |
| 17 |
|
APS Zakynthos | 4 | 0 | 0 | 4 | 0:8 | -8 | -9 |
| Play-offs | |
| Degradatie | |
| Degradatie |
