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| 30.09.2020 | 11:00 | US Lecce | - | FC Crotone | 1:2 | |
| 15:00 | AC Monza | - | AC Milan | 4:5 d.p. | ||
| 15:00 | Sampdoria | - | Torino FC | 4:2 d.p. | ||
| 15:00 | Hellas Verona | - | AS Cittadella | 6:5 d.p. | ||
| 15:00 | Bologna FC | - | Vicenza Virtus | 4:2 d.p. | ||
| 15:00 | SSC Napoli | - | Lazio Roma | 1:3 | ||
| 07.10.2020 | 11:00 | Parma Calcio 1913 | - | AC Reggiana 1919 | 2:1 n.v. | |
| 19.01.2021 | 12:20 | Frosinone Calcio | - | SPAL 2013 Ferrara | 0:5 |
