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| 16.06.2021 | 16:00 | Campobasso | - | Atletico Terme Fiuggi | 1:1 | |
| 16:00 | GSD Castelfidardo | - | Olympia Agnonese | 4:0 | ||
| 16:00 | Castelnuovo Vomano | - | FC Rieti | 1:1 | ||
| 16:00 | CynthiAlbalonga | - | Tolentino | 1:1 | ||
| 16:00 | Matese | - | ASD Pineto Calcio | 1:1 | ||
| 16:00 | Montegiorgio Calcio | - | FC Aprilia | 0:1 | ||
| 16:00 | SN Notaresco | - | Real Giulianova | 2:2 | ||
| 16:00 | Vastese Calcio | - | Porto Sant'Elpidio | 1:0 | ||
| 16:00 | Vastogirardi | - | US Recanatese | 2:2 |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Campobasso | 33 | 21 | 9 | 3 | 61:26 | 35 | 72 |
| 2 |
|
SN Notaresco | 33 | 18 | 10 | 5 | 59:32 | 27 | 64 |
| 3 |
|
CynthiAlbalonga | 33 | 13 | 14 | 6 | 48:34 | 14 | 53 |
| 4 |
|
ASD Pineto Calcio | 33 | 14 | 11 | 8 | 42:31 | 11 | 53 |
| 5 |
|
Matese | 33 | 14 | 11 | 8 | 45:38 | 7 | 53 |
| 6 |
|
GSD Castelfidardo | 33 | 13 | 13 | 7 | 42:33 | 9 | 52 |
| 7 |
|
Vastese Calcio | 33 | 12 | 13 | 8 | 45:36 | 9 | 48 |
| 8 |
|
US Recanatese | 33 | 12 | 11 | 10 | 61:45 | 16 | 47 |
| 9 |
|
Castelnuovo Vomano | 33 | 13 | 8 | 12 | 52:53 | -1 | 47 |
| 10 |
|
Montegiorgio Calcio | 33 | 13 | 6 | 14 | 40:40 | 0 | 45 |
| 11 |
|
FC Rieti | 33 | 12 | 8 | 13 | 38:41 | -3 | 44 |
| 12 |
|
FC Aprilia | 33 | 11 | 11 | 11 | 42:46 | -4 | 44 |
| 13 |
|
Atletico Terme Fiuggi | 33 | 8 | 16 | 9 | 40:38 | 2 | 40 |
| 14 |
|
Vastogirardi | 33 | 10 | 10 | 13 | 44:48 | -4 | 40 |
| 15 |
|
Tolentino | 33 | 8 | 13 | 12 | 49:51 | -2 | 37 |
| 16 |
|
Real Giulianova | 33 | 7 | 10 | 16 | 33:49 | -16 | 31 |
| 17 |
|
Porto Sant'Elpidio | 33 | 3 | 5 | 25 | 20:63 | -43 | 14 |
| 18 |
|
Olympia Agnonese | 33 | 3 | 5 | 25 | 23:80 | -57 | 14 |
| Promotie | |
| Play-offs | |
| Degradatie |
