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| 21.11.2021 | 16:00 | F91 Dudelange | - | UNA Strassen | 1:1 (1:0) | |
| 16:00 | Progrès Niedercorn | - | US Mondorf | 3:1 (0:1) | ||
| 16:00 | RM Hamm Benfica | - | FC Rodange 91 | 1:2 (0:1) | ||
| 16:00 | US Hostert | - | Victoria Rosport | 1:3 (0:1) | ||
| 16:00 | Jeunesse Esch | - | CS FOLA Esch | 3:3 (2:2) | ||
| 16:00 | RFCU Luxemburg | - | FC Differdange 03 | 3:1 (1:0) | ||
| 16:00 | Union Titus Pétange | - | Etzella Ettelbruck | 4:1 (2:0) | ||
| 16:00 | FC Wiltz 71 | - | Swift Hesperange | 2:3 (1:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
F91 Dudelange | 12 | 8 | 3 | 1 | 34:14 | 20 | 27 |
| 2 |
|
RFCU Luxemburg | 12 | 9 | 0 | 3 | 28:16 | 12 | 27 |
| 3 |
|
UNA Strassen | 12 | 8 | 2 | 2 | 24:13 | 11 | 26 |
| 4 |
|
Progrès Niedercorn | 12 | 7 | 2 | 3 | 21:14 | 7 | 23 |
| 5 |
|
Swift Hesperange | 12 | 6 | 3 | 3 | 26:14 | 12 | 21 |
| 6 |
|
CS FOLA Esch | 12 | 5 | 5 | 2 | 21:19 | 2 | 20 |
| 7 |
|
Union Titus Pétange | 12 | 6 | 0 | 6 | 22:15 | 7 | 18 |
| 8 |
|
FC Differdange 03 | 12 | 5 | 3 | 4 | 18:16 | 2 | 18 |
| 9 |
|
Victoria Rosport | 12 | 5 | 2 | 5 | 23:22 | 1 | 17 |
| 10 |
|
US Hostert | 12 | 5 | 1 | 6 | 24:26 | -2 | 16 |
| 11 |
|
US Mondorf | 12 | 5 | 1 | 6 | 14:17 | -3 | 16 |
| 12 |
|
Jeunesse Esch | 12 | 4 | 2 | 6 | 15:16 | -1 | 14 |
| 13 |
|
FC Wiltz 71 | 12 | 4 | 1 | 7 | 18:25 | -7 | 13 |
| 14 |
|
Etzella Ettelbruck | 12 | 4 | 0 | 8 | 21:31 | -10 | 12 |
| 15 |
|
FC Rodange 91 | 12 | 1 | 1 | 10 | 11:29 | -18 | 4 |
| 16 |
|
RM Hamm Benfica | 12 | 1 | 0 | 11 | 6:39 | -33 | 3 |
| Champions League Kwali. | |
| Promotie en degradatie | |
| Degradatie |
