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| U | CF América | - | CF Monterrey | 1:4 (0:3) | ||
| R | CF Monterrey | - | CF América | 3:2 (1:1) | ||
| U: 05.12.2020 00:00 | R: 08.12.2020 04:00 | Winnaars: CF Monterrey | ||||
| U | Gallos Blancos | - | UANL Tigres | 0:2 (0:1) | ||
| R | UANL Tigres | - | Gallos Blancos | 2:0 (1:0) | ||
| U: 05.12.2020 02:00 | R: 08.12.2020 02:00 | Winnaars: UANL Tigres | ||||
