 |
 |
|
| 06.01.2022 | 02:00 | Alebrijes de Oaxaca | - | Cancún FC | 2:0 (2:0) | |
| 07.01.2022 | 00:00 | Club Celaya | - | Tepatitlán | 1:1 (0:1) | |
| 02:05 | Pumas Tabasco | - | CF Monterrey II | 0:1 (0:1) | ||
| 08.01.2022 | 00:00 | Tapatío | - | Mineros de Zacatecas | 2:0 (0:0) | |
| 09.01.2022 | 02:00 | Venados FC | - | Atlante | 1:0 (0:0) | |
| 10.01.2022 | 00:00 | Coyotes de Tlaxcala | - | Atlético Morelia | 0:4 (0:2) | |
| 03:00 | Correcaminos UAT | - | Dorados de Sinaloa | 1:2 (1:0) | ||
| 14.02.2022 | 04:00 | Cimarrones de Sonora | - | Leones Negros | 2:3 (2:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Atlético Morelia | 1 | 1 | 0 | 0 | 4:0 | 4 | 3 |
| 2 |
|
Alebrijes de Oaxaca | 1 | 1 | 0 | 0 | 2:0 | 2 | 3 |
|
Tapatío | 1 | 1 | 0 | 0 | 2:0 | 2 | 3 | |
| 4 |
|
Leones Negros | 1 | 1 | 0 | 0 | 3:2 | 1 | 3 |
| 5 |
|
Dorados de Sinaloa | 1 | 1 | 0 | 0 | 2:1 | 1 | 3 |
| 6 |
|
CF Monterrey II | 1 | 1 | 0 | 0 | 1:0 | 1 | 3 |
|
Venados FC | 1 | 1 | 0 | 0 | 1:0 | 1 | 3 | |
| 8 |
|
Club Celaya | 1 | 0 | 1 | 0 | 1:1 | 0 | 1 |
|
Tepatitlán | 1 | 0 | 1 | 0 | 1:1 | 0 | 1 | |
| 10 |
|
TM Fútbol Club | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| 11 |
|
Cimarrones de Sonora | 1 | 0 | 0 | 1 | 2:3 | -1 | 0 |
| 12 |
|
Correcaminos UAT | 1 | 0 | 0 | 1 | 1:2 | -1 | 0 |
| 13 |
|
Atlante | 1 | 0 | 0 | 1 | 0:1 | -1 | 0 |
|
Pumas Tabasco | 1 | 0 | 0 | 1 | 0:1 | -1 | 0 | |
| 15 |
|
Cancún FC | 1 | 0 | 0 | 1 | 0:2 | -2 | 0 |
|
Mineros de Zacatecas | 1 | 0 | 0 | 1 | 0:2 | -2 | 0 | |
| 17 |
|
Coyotes de Tlaxcala | 1 | 0 | 0 | 1 | 0:4 | -4 | 0 |
| Play-offs | |
| Play-offs |
