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| U | Leones Negros | - | Atlante | 1:1 (0:1) | ||
| R | Atlante | - | Leones Negros | 1:0 (0:0) | ||
| U: 03.11.2022 02:00 | R: 06.11.2022 02:00 | Winnaars: Atlante | ||||
| U | Cimarrones de Sonora | - | Club Celaya | 0:0 (0:0) | ||
| R | Club Celaya | - | Cimarrones de Sonora | 3:1 (1:0) | ||
| U: 03.11.2022 03:10 | R: 05.11.2022 22:00 | Winnaars: Club Celaya | ||||
