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| 09.11.2018 | 22:00 | Cruz Azul Hidalgo | - | Reboceros de La Piedad | 3:0 (3:0) | |
| 10.11.2018 | 18:00 | Cimarrones de Sonora II | - | Tecos Fútbol Club | 0:4 (0:4) | |
| 19:00 | Monarcas Morelia II | - | Coras de Nayarit | 2:3 (2:3) | ||
| 22:00 | Real Zamora | - | Pioneros de Cancún | 2:0 (2:0) | ||
| 22:30 | Tuzos de la UAZ | - | Albinegros Orizaba | 0:1 (0:1) | ||
| 23:00 | Sporting Canamy | - | Deportivo Toluca II | 1:0 (1:0) | ||
| 23:00 | Gavilanes de Matamoros | - | Dorados UACH | 1:0 (1:0) | ||
| 23:00 | Cocodrilos de Tabasco | - | Coyotes de Tlaxcala | 1:1 (1:1) | ||
| 23:00 | Tepatitlán | - | Atlético Reynosa | 1:3 (1:3) | ||
| 11.11.2018 | 00:00 | Correcaminos UAT II | - | Loros UCOL | 0:2 (0:2) | |
| 00:00 | Yalmakan FC | - | Tuxtla FC | 2:3 (2:3) | ||
| 00:00 | Pacific F. C. | - | Alacranes de Durango | 0:0 (0:0) | ||
| 02:00 | Club Irapuato | - | Pumas UNAM II | 1:1 (1:1) | ||
| 02:00 | Inter Playa | - | CF América II | 2:0 (2:0) | ||
| 18:00 | Club Necaxa II | - | Murciélagos FC | 2:1 (2:1) | ||
| 19:00 | Leones Negros II | - | Deportivo Guadalajara II | 1:2 (1:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 12 | 9 | 2 | 1 | 23:8 | 15 | 33 |
| 2 |
|
Deportivo Guadalajara II | 12 | 7 | 4 | 1 | 20:9 | 11 | 29 |
| 3 |
|
Loros UCOL | 12 | 6 | 2 | 4 | 24:11 | 13 | 26 |
| 4 |
|
Murciélagos FC | 12 | 7 | 2 | 3 | 21:12 | 9 | 26 |
| 5 |
|
Tuxtla FC | 12 | 7 | 2 | 3 | 24:13 | 11 | 25 |
| 6 |
|
Cruz Azul Hidalgo | 12 | 6 | 3 | 3 | 20:13 | 7 | 25 |
| 7 |
|
Gavilanes de Matamoros | 12 | 7 | 2 | 3 | 17:12 | 5 | 25 |
| 8 |
|
Club Necaxa II | 12 | 5 | 6 | 1 | 13:10 | 3 | 24 |
| 9 |
|
Tepatitlán | 12 | 6 | 3 | 3 | 19:16 | 3 | 23 |
| 10 |
|
Tuzos de la UAZ | 12 | 5 | 5 | 2 | 18:14 | 4 | 22 |
| 11 |
|
Inter Playa | 12 | 6 | 2 | 4 | 18:15 | 3 | 22 |
| 12 |
|
Coras de Nayarit | 12 | 5 | 4 | 3 | 17:15 | 2 | 21 |
| 13 |
|
Monarcas Morelia II | 12 | 5 | 3 | 4 | 23:11 | 12 | 19 |
| 14 |
|
Deportivo Toluca II | 12 | 4 | 5 | 3 | 20:17 | 3 | 19 |
| 15 |
|
Correcaminos UAT II | 12 | 4 | 4 | 4 | 14:13 | 1 | 19 |
| 16 |
|
Tecos Fútbol Club | 12 | 4 | 2 | 6 | 15:17 | -2 | 19 |
| 17 |
|
Real Zamora | 12 | 5 | 1 | 6 | 15:18 | -3 | 18 |
| 18 |
|
Sporting Canamy | 12 | 5 | 2 | 5 | 19:23 | -4 | 18 |
| 19 |
|
Atlético Reynosa | 12 | 3 | 4 | 5 | 14:12 | 2 | 17 |
| 20 |
|
Pumas UNAM II | 12 | 4 | 2 | 6 | 17:17 | 0 | 17 |
| 21 |
|
Coyotes de Tlaxcala | 12 | 3 | 6 | 3 | 13:13 | 0 | 17 |
| 22 |
|
Albinegros Orizaba | 12 | 4 | 4 | 4 | 6:10 | -4 | 17 |
| 23 |
|
Reboceros de La Piedad | 12 | 3 | 3 | 6 | 14:21 | -7 | 16 |
| 24 |
|
Dorados UACH | 12 | 3 | 3 | 6 | 10:17 | -7 | 16 |
| 25 |
|
Leones Negros II | 12 | 3 | 4 | 5 | 18:19 | -1 | 14 |
| 26 |
|
Cocodrilos de Tabasco | 12 | 2 | 5 | 5 | 13:16 | -3 | 14 |
| 27 |
|
CF América II | 12 | 2 | 5 | 5 | 13:21 | -8 | 13 |
| 28 |
|
Yalmakan FC | 12 | 2 | 4 | 6 | 12:17 | -5 | 12 |
| 29 |
|
Alacranes de Durango | 12 | 2 | 5 | 5 | 8:16 | -8 | 12 |
| 30 |
|
Pacific F. C. | 12 | 2 | 4 | 6 | 12:25 | -13 | 12 |
| 31 |
|
Pioneros de Cancún | 12 | 1 | 5 | 6 | 13:22 | -9 | 10 |
| 32 |
|
Cimarrones de Sonora II | 12 | 0 | 2 | 10 | 5:35 | -30 | 2 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
