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| 16.11.2018 | 17:00 | Pumas UNAM II | - | Inter Playa | 2:1 (2:1) | |
| 17.11.2018 | 01:00 | Tecos Fútbol Club | - | Alacranes de Durango | 0:0 (0:0) | |
| 02:30 | Atlético Reynosa | - | Leones Negros II | 3:0 (3:0) | ||
| 03:30 | Dorados UACH | - | Correcaminos UAT II | 0:0 (0:0) | ||
| 04:00 | Coras de Nayarit | - | Gavilanes de Matamoros | 2:2 (2:2) | ||
| 04:00 | Murciélagos FC | - | Tepatitlán | 0:0 (0:0) | ||
| 18:00 | Coyotes de Tlaxcala | - | Real Zamora | 0:0 (0:0) | ||
| 19:00 | Cimarrones de Sonora II | - | Club Necaxa II | 0:2 (0:2) | ||
| 19:15 | Deportivo Toluca II | - | Tuzos de la UAZ | 3:0 (3:0) | ||
| 22:00 | Albinegros Orizaba | - | Club Irapuato | 0:2 (0:2) | ||
| 22:00 | Tuxtla FC | - | CF América II | 1:1 (1:1) | ||
| 22:00 | Pioneros de Cancún | - | Sporting Canamy | 1:1 (1:1) | ||
| 23:00 | Loros UCOL | - | Pacific F. C. | 3:0 (3:0) | ||
| 23:00 | Yalmakan FC | - | Cruz Azul Hidalgo | 0:2 (0:2) | ||
| 18.11.2018 | 17:00 | Deportivo Guadalajara II | - | Monarcas Morelia II | 1:1 (1:1) | |
| 22:30 | Reboceros de La Piedad | - | Cocodrilos de Tabasco | 2:2 (2:2) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 13 | 10 | 2 | 1 | 25:8 | 17 | 36 |
| 2 |
|
Deportivo Guadalajara II | 13 | 7 | 5 | 1 | 21:10 | 11 | 30 |
| 3 |
|
Loros UCOL | 13 | 7 | 2 | 4 | 27:11 | 16 | 29 |
| 4 |
|
Cruz Azul Hidalgo | 13 | 7 | 3 | 3 | 22:13 | 9 | 28 |
| 5 |
|
Murciélagos FC | 13 | 7 | 3 | 3 | 21:12 | 9 | 27 |
| 6 |
|
Club Necaxa II | 13 | 6 | 6 | 1 | 15:10 | 5 | 27 |
| 7 |
|
Tuxtla FC | 13 | 7 | 3 | 3 | 25:14 | 11 | 26 |
| 8 |
|
Gavilanes de Matamoros | 13 | 7 | 3 | 3 | 19:14 | 5 | 26 |
| 9 |
|
Tepatitlán | 13 | 6 | 4 | 3 | 19:16 | 3 | 24 |
| 10 |
|
Deportivo Toluca II | 13 | 5 | 5 | 3 | 23:17 | 6 | 22 |
| 11 |
|
Coras de Nayarit | 13 | 5 | 5 | 3 | 19:17 | 2 | 22 |
|
Inter Playa | 13 | 6 | 2 | 5 | 19:17 | 2 | 22 | |
| 13 |
|
Tuzos de la UAZ | 13 | 5 | 5 | 3 | 18:17 | 1 | 22 |
| 14 |
|
Monarcas Morelia II | 13 | 5 | 4 | 4 | 24:12 | 12 | 20 |
| 15 |
|
Atlético Reynosa | 13 | 4 | 4 | 5 | 17:12 | 5 | 20 |
| 16 |
|
Pumas UNAM II | 13 | 5 | 2 | 6 | 19:18 | 1 | 20 |
| 17 |
|
Correcaminos UAT II | 13 | 4 | 5 | 4 | 14:13 | 1 | 20 |
| 18 |
|
Tecos Fútbol Club | 13 | 4 | 3 | 6 | 15:17 | -2 | 20 |
| 19 |
|
Real Zamora | 13 | 5 | 2 | 6 | 15:18 | -3 | 19 |
| 20 |
|
Sporting Canamy | 13 | 5 | 3 | 5 | 20:24 | -4 | 19 |
| 21 |
|
Coyotes de Tlaxcala | 13 | 3 | 7 | 3 | 13:13 | 0 | 18 |
| 22 |
|
Albinegros Orizaba | 13 | 4 | 4 | 5 | 6:12 | -6 | 17 |
| 23 |
|
Reboceros de La Piedad | 13 | 3 | 4 | 6 | 16:23 | -7 | 17 |
| 24 |
|
Dorados UACH | 13 | 3 | 4 | 6 | 10:17 | -7 | 17 |
| 25 |
|
Cocodrilos de Tabasco | 13 | 2 | 6 | 5 | 15:18 | -3 | 15 |
| 26 |
|
Leones Negros II | 13 | 3 | 4 | 6 | 18:22 | -4 | 14 |
| 27 |
|
CF América II | 13 | 2 | 6 | 5 | 14:22 | -8 | 14 |
| 28 |
|
Alacranes de Durango | 13 | 2 | 6 | 5 | 8:16 | -8 | 13 |
| 29 |
|
Yalmakan FC | 13 | 2 | 4 | 7 | 12:19 | -7 | 12 |
| 30 |
|
Pacific F. C. | 13 | 2 | 4 | 7 | 12:28 | -16 | 12 |
| 31 |
|
Pioneros de Cancún | 13 | 1 | 6 | 6 | 14:23 | -9 | 11 |
| 32 |
|
Cimarrones de Sonora II | 13 | 0 | 2 | 11 | 5:37 | -32 | 2 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
