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| 30.11.2018 | 17:00 | Pumas UNAM II | - | Tuxtla FC | 2:1 (1:1) | |
| 22:00 | Cruz Azul Hidalgo | - | Cocodrilos de Tabasco | 1:0 (1:0) | ||
| 23:00 | Club Necaxa II | - | Tepatitlán | 2:1 (0:1) | ||
| 01.12.2018 | 02:30 | Atlético Reynosa | - | Gavilanes de Matamoros | 1:0 (0:0) | |
| 02:30 | Dorados UACH | - | Alacranes de Durango | 1:0 (1:0) | ||
| 03:00 | Coras de Nayarit | - | Pacific F. C. | 4:1 (1:1) | ||
| 03:00 | Murciélagos FC | - | Monarcas Morelia II | 4:2 (2:2) | ||
| 18:00 | Cimarrones de Sonora II | - | Leones Negros II | 0:1 (0:1) | ||
| 18:00 | Coyotes de Tlaxcala | - | Tuzos de la UAZ | 2:2 (0:1) | ||
| 19:15 | Deportivo Toluca II | - | Inter Playa | 0:0 (0:0) | ||
| 22:00 | Albinegros Orizaba | - | CF América II | 1:0 (1:0) | ||
| 23:00 | Loros UCOL | - | Tecos Fútbol Club | 5:4 (3:2) | ||
| 02.12.2018 | 00:00 | Pioneros de Cancún | - | Club Irapuato | 0:1 (0:0) | |
| 17:00 | Deportivo Guadalajara II | - | Correcaminos UAT II | 4:1 (2:1) | ||
| 22:30 | Reboceros de La Piedad | - | Sporting Canamy | 1:1 (1:1) | ||
| 04.12.2018 | 01:00 | Yalmakan FC | - | Real Zamora | 1:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 15 | 12 | 2 | 1 | 27:8 | 19 | 42 |
| 2 |
|
Loros UCOL | 15 | 9 | 2 | 4 | 34:15 | 19 | 35 |
| 3 |
|
Deportivo Guadalajara II | 15 | 8 | 6 | 1 | 26:12 | 14 | 34 |
| 4 |
|
Murciélagos FC | 15 | 9 | 3 | 3 | 28:15 | 13 | 33 |
| 5 |
|
Cruz Azul Hidalgo | 15 | 8 | 3 | 4 | 23:15 | 8 | 31 |
| 6 |
|
Club Necaxa II | 15 | 7 | 7 | 1 | 18:12 | 6 | 31 |
| 7 |
|
Tuxtla FC | 15 | 8 | 3 | 4 | 28:16 | 12 | 29 |
| 8 |
|
Tepatitlán | 15 | 7 | 4 | 4 | 24:18 | 6 | 27 |
| 9 |
|
Gavilanes de Matamoros | 15 | 7 | 4 | 4 | 20:16 | 4 | 27 |
| 10 |
|
Atlético Reynosa | 15 | 6 | 4 | 5 | 19:12 | 7 | 26 |
| 11 |
|
Inter Playa | 15 | 7 | 3 | 5 | 22:18 | 4 | 26 |
| 12 |
|
Pumas UNAM II | 15 | 7 | 2 | 6 | 23:20 | 3 | 26 |
| 13 |
|
Tuzos de la UAZ | 15 | 6 | 6 | 3 | 21:19 | 2 | 26 |
| 14 |
|
Coras de Nayarit | 15 | 6 | 5 | 4 | 23:19 | 4 | 25 |
| 15 |
|
Deportivo Toluca II | 15 | 5 | 6 | 4 | 23:18 | 5 | 23 |
| 16 |
|
Correcaminos UAT II | 15 | 5 | 5 | 5 | 16:17 | -1 | 23 |
| 17 |
|
Real Zamora | 15 | 6 | 3 | 6 | 17:19 | -2 | 23 |
| 18 |
|
Coyotes de Tlaxcala | 15 | 4 | 8 | 3 | 16:15 | 1 | 22 |
| 19 |
|
Tecos Fútbol Club | 15 | 4 | 4 | 7 | 20:23 | -3 | 21 |
| 20 |
|
Monarcas Morelia II | 15 | 5 | 4 | 6 | 26:17 | 9 | 20 |
| 21 |
|
Sporting Canamy | 15 | 5 | 4 | 6 | 21:26 | -5 | 20 |
| 22 |
|
Dorados UACH | 15 | 4 | 4 | 7 | 12:19 | -7 | 20 |
| 23 |
|
Albinegros Orizaba | 15 | 5 | 4 | 6 | 8:15 | -7 | 20 |
| 24 |
|
Reboceros de La Piedad | 15 | 3 | 5 | 7 | 17:25 | -8 | 18 |
| 25 |
|
Leones Negros II | 15 | 4 | 4 | 7 | 20:25 | -5 | 17 |
| 26 |
|
Cocodrilos de Tabasco | 15 | 2 | 7 | 6 | 17:21 | -4 | 16 |
| 27 |
|
Pacific F. C. | 15 | 3 | 4 | 8 | 15:33 | -18 | 15 |
| 28 |
|
Yalmakan FC | 15 | 2 | 6 | 7 | 15:22 | -7 | 14 |
| 29 |
|
CF América II | 15 | 2 | 6 | 7 | 15:25 | -10 | 14 |
| 30 |
|
Alacranes de Durango | 15 | 2 | 6 | 7 | 8:19 | -11 | 13 |
| 31 |
|
Pioneros de Cancún | 15 | 1 | 6 | 8 | 14:25 | -11 | 11 |
| 32 |
|
Cimarrones de Sonora II | 15 | 0 | 2 | 13 | 5:42 | -37 | 2 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
