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| 15.02.2019 | 17:00 | Pumas UNAM II | - | Yalmakan FC | 0:0 (0:0) | |
| 17:00 | CF América II | - | Cruz Azul Hidalgo | 2:0 (1:0) | ||
| 16.02.2019 | 01:00 | Tecos Fútbol Club | - | Deportivo Guadalajara II | 0:1 (0:1) | |
| 03:00 | Coras de Nayarit | - | Atlético Reynosa | 0:0 (0:0) | ||
| 03:00 | Alacranes de Durango | - | Club Necaxa II | 2:0 (2:0) | ||
| 03:10 | Pacific F. C. | - | Tepatitlán | 1:2 (0:1) | ||
| 19:15 | Deportivo Toluca II | - | Coyotes de Tlaxcala | 1:4 (1:2) | ||
| 22:00 | Tuxtla FC | - | Pioneros de Cancún | 1:1 (0:1) | ||
| 22:00 | Albinegros Orizaba | - | Reboceros de La Piedad | 1:4 (1:4) | ||
| 22:30 | Tuzos de la UAZ | - | Sporting Canamy | 5:0 (2:0) | ||
| 23:00 | Dorados UACH | - | Murciélagos FC | 1:0 (0:0) | ||
| 23:00 | Loros UCOL | - | Cimarrones de Sonora II | 11:0 (6:0) | ||
| 23:00 | Gavilanes de Matamoros | - | Monarcas Morelia II | 1:1 (1:0) | ||
| 17.02.2019 | 00:00 | Inter Playa | - | Cocodrilos de Tabasco | 0:0 (0:0) | |
| 02:00 | Club Irapuato | - | Real Zamora | 3:0 (1:0) | ||
| 19.02.2019 | 00:00 | Correcaminos UAT II | - | Leones Negros II | 2:0 (2:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 21 | 15 | 4 | 2 | 36:13 | 23 | 53 |
| 2 |
|
Deportivo Guadalajara II | 21 | 11 | 8 | 2 | 34:20 | 14 | 45 |
| 3 |
|
Loros UCOL | 21 | 11 | 4 | 6 | 51:23 | 28 | 43 |
| 4 |
|
Murciélagos FC | 21 | 12 | 4 | 5 | 41:22 | 19 | 43 |
| 5 |
|
Club Necaxa II | 21 | 11 | 7 | 3 | 26:17 | 9 | 43 |
| 6 |
|
Tuxtla FC | 21 | 12 | 4 | 5 | 36:19 | 17 | 42 |
| 7 |
|
Tepatitlán | 21 | 11 | 6 | 4 | 37:26 | 11 | 41 |
| 8 |
|
Atlético Reynosa | 21 | 9 | 6 | 6 | 25:15 | 10 | 37 |
| 9 |
|
Tuzos de la UAZ | 21 | 9 | 8 | 4 | 33:25 | 8 | 37 |
| 10 |
|
Cruz Azul Hidalgo | 21 | 9 | 5 | 7 | 26:20 | 6 | 36 |
| 11 |
|
Pumas UNAM II | 21 | 9 | 5 | 7 | 29:24 | 5 | 35 |
| 12 |
|
Dorados UACH | 21 | 8 | 6 | 7 | 23:21 | 2 | 34 |
| 13 |
|
Inter Playa | 21 | 8 | 7 | 6 | 26:22 | 4 | 33 |
| 14 |
|
Coras de Nayarit | 21 | 8 | 7 | 6 | 28:25 | 3 | 33 |
| 15 |
|
Real Zamora | 21 | 9 | 4 | 8 | 25:26 | -1 | 33 |
| 16 |
|
Gavilanes de Matamoros | 21 | 8 | 6 | 7 | 28:25 | 3 | 32 |
| 17 |
|
Deportivo Toluca II | 21 | 8 | 6 | 7 | 31:29 | 2 | 32 |
| 18 |
|
Correcaminos UAT II | 21 | 7 | 6 | 8 | 24:27 | -3 | 30 |
| 19 |
|
Monarcas Morelia II | 21 | 7 | 7 | 7 | 34:24 | 10 | 29 |
| 20 |
|
Coyotes de Tlaxcala | 21 | 5 | 12 | 4 | 26:23 | 3 | 29 |
| 21 |
|
Reboceros de La Piedad | 21 | 5 | 8 | 8 | 28:32 | -4 | 27 |
| 22 |
|
Tecos Fútbol Club | 21 | 5 | 5 | 11 | 27:32 | -5 | 25 |
| 23 |
|
Cocodrilos de Tabasco | 21 | 4 | 9 | 8 | 20:25 | -5 | 24 |
| 24 |
|
Albinegros Orizaba | 21 | 6 | 5 | 10 | 13:28 | -15 | 24 |
| 25 |
|
Yalmakan FC | 21 | 4 | 8 | 9 | 23:30 | -7 | 22 |
| 26 |
|
Sporting Canamy | 21 | 5 | 6 | 10 | 23:39 | -16 | 22 |
| 27 |
|
Alacranes de Durango | 21 | 4 | 8 | 9 | 16:26 | -10 | 21 |
| 28 |
|
CF América II | 21 | 3 | 9 | 9 | 23:33 | -10 | 20 |
| 29 |
|
Leones Negros II | 21 | 4 | 6 | 11 | 21:33 | -12 | 19 |
| 30 |
|
Pioneros de Cancún | 21 | 2 | 10 | 9 | 18:28 | -10 | 18 |
| 31 |
|
Pacific F. C. | 21 | 3 | 5 | 13 | 19:46 | -27 | 16 |
| 32 |
|
Cimarrones de Sonora II | 21 | 2 | 3 | 16 | 10:62 | -52 | 9 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
