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| 22.03.2019 | 18:00 | Club Necaxa II | - | Atlético Reynosa | 1:1 (0:0) | |
| 22:00 | Cruz Azul Hidalgo | - | Coyotes de Tlaxcala | 3:1 (2:1) | ||
| 23.03.2019 | 03:10 | Pacific F. C. | - | Tecos Fútbol Club | 1:0 (1:0) | |
| 18:00 | Cimarrones de Sonora II | - | Murciélagos FC | 3:4 (2:0) | ||
| 19:00 | Monarcas Morelia II | - | Dorados UACH | 1:2 (1:1) | ||
| 22:00 | Real Zamora | - | Deportivo Toluca II | 0:0 (0:0) | ||
| 22:30 | Tuzos de la UAZ | - | Pumas UNAM II | 2:0 (2:0) | ||
| 23:00 | Sporting Canamy | - | Albinegros Orizaba | 1:1 (0:0) | ||
| 23:00 | Tepatitlán | - | Deportivo Guadalajara II | 2:1 (0:1) | ||
| 23:00 | Yalmakan FC | - | Reboceros de La Piedad | 0:1 (0:1) | ||
| 23:00 | Cocodrilos de Tabasco | - | Pioneros de Cancún | 0:1 (0:1) | ||
| 24.03.2019 | 00:00 | Correcaminos UAT II | - | Alacranes de Durango | 3:1 (0:0) | |
| 00:00 | Gavilanes de Matamoros | - | Loros UCOL | 1:1 (1:0) | ||
| 00:00 | Inter Playa | - | Tuxtla FC | 1:2 (0:1) | ||
| 02:00 | Club Irapuato | - | CF América II | 5:0 (1:0) | ||
| 26.03.2019 | 00:00 | Leones Negros II | - | Coras de Nayarit | 0:3 (0:1) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 26 | 19 | 5 | 2 | 49:14 | 35 | 66 |
| 2 |
|
Loros UCOL | 26 | 14 | 5 | 7 | 64:30 | 34 | 53 |
| 3 |
|
Deportivo Guadalajara II | 26 | 13 | 9 | 4 | 38:26 | 12 | 52 |
| 4 |
|
Tepatitlán | 26 | 14 | 6 | 6 | 46:35 | 11 | 50 |
| 5 |
|
Murciélagos FC | 26 | 13 | 6 | 7 | 48:30 | 18 | 48 |
| 6 |
|
Club Necaxa II | 26 | 12 | 9 | 5 | 31:25 | 6 | 48 |
| 7 |
|
Pumas UNAM II | 26 | 13 | 5 | 8 | 41:28 | 13 | 47 |
| 8 |
|
Atlético Reynosa | 26 | 11 | 9 | 6 | 35:19 | 16 | 46 |
| 9 |
|
Tuxtla FC | 26 | 13 | 5 | 8 | 39:25 | 14 | 46 |
| 10 |
|
Tuzos de la UAZ | 26 | 12 | 8 | 6 | 38:30 | 8 | 46 |
| 11 |
|
Dorados UACH | 26 | 12 | 6 | 8 | 32:26 | 6 | 46 |
| 12 |
|
Coras de Nayarit | 26 | 12 | 7 | 7 | 38:28 | 10 | 45 |
| 13 |
|
Deportivo Toluca II | 26 | 11 | 8 | 7 | 37:31 | 6 | 43 |
| 14 |
|
Cruz Azul Hidalgo | 26 | 11 | 6 | 9 | 33:28 | 5 | 43 |
| 15 |
|
Gavilanes de Matamoros | 26 | 10 | 8 | 8 | 36:30 | 6 | 40 |
| 16 |
|
Correcaminos UAT II | 26 | 10 | 7 | 9 | 37:38 | -1 | 40 |
| 17 |
|
Real Zamora | 26 | 11 | 5 | 10 | 33:34 | -1 | 40 |
| 18 |
|
Inter Playa | 26 | 9 | 8 | 9 | 29:28 | 1 | 37 |
| 19 |
|
Coyotes de Tlaxcala | 26 | 7 | 12 | 7 | 32:31 | 1 | 35 |
| 20 |
|
Monarcas Morelia II | 26 | 8 | 9 | 9 | 43:32 | 11 | 34 |
| 21 |
|
Reboceros de La Piedad | 26 | 7 | 9 | 10 | 30:35 | -5 | 34 |
| 22 |
|
Albinegros Orizaba | 26 | 9 | 6 | 11 | 23:31 | -8 | 34 |
| 23 |
|
Pioneros de Cancún | 26 | 5 | 11 | 10 | 24:32 | -8 | 28 |
| 24 |
|
Cocodrilos de Tabasco | 26 | 5 | 10 | 11 | 21:29 | -8 | 28 |
| 25 |
|
Tecos Fútbol Club | 26 | 5 | 8 | 13 | 34:43 | -9 | 28 |
| 26 |
|
Leones Negros II | 26 | 7 | 6 | 13 | 32:45 | -13 | 28 |
| 27 |
|
Sporting Canamy | 26 | 6 | 7 | 13 | 27:50 | -23 | 26 |
| 28 |
|
CF América II | 26 | 4 | 10 | 12 | 26:44 | -18 | 24 |
| 29 |
|
Yalmakan FC | 26 | 4 | 9 | 13 | 26:38 | -12 | 23 |
| 30 |
|
Alacranes de Durango | 26 | 4 | 10 | 12 | 21:36 | -15 | 23 |
| 31 |
|
Pacific F. C. | 26 | 4 | 6 | 16 | 26:58 | -32 | 20 |
| 32 |
|
Cimarrones de Sonora II | 26 | 2 | 3 | 21 | 13:73 | -60 | 9 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
