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| 05.04.2019 | 17:00 | CF América II | - | Tuxtla FC | 1:1 (1:0) | |
| 06.04.2019 | 03:00 | Alacranes de Durango | - | Tecos Fútbol Club | 1:2 (0:0) | |
| 03:10 | Pacific F. C. | - | Loros UCOL | 2:2 (0:1) | ||
| 19:00 | Monarcas Morelia II | - | Deportivo Guadalajara II | 0:2 (0:0) | ||
| 22:00 | Cruz Azul Hidalgo | - | Yalmakan FC | 2:0 (0:0) | ||
| 22:00 | Inter Playa | - | Pumas UNAM II | 2:1 (0:0) | ||
| 23:00 | Real Zamora | - | Coyotes de Tlaxcala | 2:0 (0:0) | ||
| 23:00 | Sporting Canamy | - | Pioneros de Cancún | 0:1 (0:1) | ||
| 23:00 | Cocodrilos de Tabasco | - | Reboceros de La Piedad | 1:3 (0:2) | ||
| 07.04.2019 | 00:00 | Correcaminos UAT II | - | Dorados UACH | 1:4 (0:0) | |
| 00:00 | Gavilanes de Matamoros | - | Coras de Nayarit | 1:0 (1:0) | ||
| 00:00 | Tepatitlán | - | Murciélagos FC | 1:2 (0:0) | ||
| 02:00 | Club Irapuato | - | Albinegros Orizaba | 4:1 (2:1) | ||
| 18:00 | Club Necaxa II | - | Cimarrones de Sonora II | 4:3 (3:2) | ||
| 19:00 | Leones Negros II | - | Atlético Reynosa | 0:2 (0:1) | ||
| 09.04.2019 | 00:00 | Tuzos de la UAZ | - | Deportivo Toluca II | 4:1 (1:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 28 | 20 | 5 | 3 | 55:18 | 37 | 69 |
| 2 |
|
Deportivo Guadalajara II | 28 | 15 | 9 | 4 | 42:27 | 15 | 58 |
| 3 |
|
Loros UCOL | 28 | 15 | 6 | 7 | 68:32 | 36 | 57 |
| 4 |
|
Murciélagos FC | 28 | 15 | 6 | 7 | 52:32 | 20 | 54 |
| 5 |
|
Atlético Reynosa | 28 | 13 | 9 | 6 | 40:21 | 19 | 52 |
| 6 |
|
Tuzos de la UAZ | 28 | 14 | 8 | 6 | 43:31 | 12 | 52 |
| 7 |
|
Club Necaxa II | 28 | 13 | 9 | 6 | 36:30 | 6 | 51 |
| 8 |
|
Tuxtla FC | 28 | 14 | 6 | 8 | 44:27 | 17 | 50 |
| 9 |
|
Pumas UNAM II | 28 | 14 | 5 | 9 | 45:32 | 13 | 50 |
| 10 |
|
Tepatitlán | 28 | 14 | 6 | 8 | 49:40 | 9 | 50 |
| 11 |
|
Dorados UACH | 28 | 13 | 6 | 9 | 37:29 | 8 | 49 |
| 12 |
|
Coras de Nayarit | 28 | 13 | 7 | 8 | 39:29 | 10 | 48 |
| 13 |
|
Gavilanes de Matamoros | 28 | 12 | 8 | 8 | 39:31 | 8 | 46 |
| 14 |
|
Cruz Azul Hidalgo | 28 | 12 | 6 | 10 | 35:30 | 5 | 46 |
| 15 |
|
Inter Playa | 28 | 11 | 8 | 9 | 32:29 | 3 | 43 |
| 16 |
|
Deportivo Toluca II | 28 | 11 | 8 | 9 | 40:38 | 2 | 43 |
| 17 |
|
Real Zamora | 28 | 12 | 5 | 11 | 37:37 | 0 | 43 |
| 18 |
|
Reboceros de La Piedad | 28 | 9 | 9 | 10 | 35:36 | -1 | 40 |
| 19 |
|
Correcaminos UAT II | 28 | 10 | 7 | 11 | 38:44 | -6 | 40 |
| 20 |
|
Coyotes de Tlaxcala | 28 | 8 | 12 | 8 | 37:33 | 4 | 38 |
| 21 |
|
Monarcas Morelia II | 28 | 8 | 9 | 11 | 43:35 | 8 | 34 |
| 22 |
|
Tecos Fútbol Club | 28 | 7 | 8 | 13 | 39:45 | -6 | 34 |
| 23 |
|
Pioneros de Cancún | 28 | 7 | 11 | 10 | 28:34 | -6 | 34 |
| 24 |
|
Albinegros Orizaba | 28 | 9 | 6 | 13 | 24:36 | -12 | 34 |
| 25 |
|
Sporting Canamy | 28 | 7 | 7 | 14 | 30:53 | -23 | 29 |
| 26 |
|
Cocodrilos de Tabasco | 28 | 5 | 10 | 13 | 22:37 | -15 | 28 |
| 27 |
|
Leones Negros II | 28 | 7 | 6 | 15 | 33:49 | -16 | 28 |
| 28 |
|
CF América II | 28 | 4 | 11 | 13 | 27:46 | -19 | 25 |
| 29 |
|
Alacranes de Durango | 28 | 4 | 11 | 13 | 24:40 | -16 | 24 |
| 30 |
|
Yalmakan FC | 28 | 4 | 9 | 15 | 27:44 | -17 | 23 |
| 31 |
|
Pacific F. C. | 28 | 4 | 8 | 16 | 30:62 | -32 | 22 |
| 32 |
|
Cimarrones de Sonora II | 28 | 2 | 3 | 23 | 17:80 | -63 | 9 |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Play-offs | |
| Degradatie |
