 |
 |
|
|
| U | Atlas Guadalajara | - | UANL Tigres | 3:0 (1:0) | ||
| R | UANL Tigres | - | Atlas Guadalajara | 4:2 (0:1) | ||
| U: 19.05.2022 04:00 | R: 22.05.2022 03:00 | Winnaars: Atlas Guadalajara | ||||
| U | CF América | - | CF Pachuca | 1:1 (0:0) | ||
| R | CF Pachuca | - | CF América | 3:0 (2:0) | ||
| U: 20.05.2022 03:00 | R: 23.05.2022 03:06 | Winnaars: CF Pachuca | ||||
