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| U | CF América | - | Deportivo Guadalajara | 1:0 (1:0) | ||
| R | Deportivo Guadalajara | - | CF América | 2:1 (0:1) | ||
| U: 05.12.2018 16:00 | R: 08.12.2018 16:00 | Winnaars: CF América | ||||
| U | Atlas Guadalajara | - | UANL Tigres | 2:2 (1:0) | ||
| R | UANL Tigres | - | Atlas Guadalajara | 2:1 (1:0) | ||
| U: 05.12.2018 18:30 | R: 08.12.2018 18:00 | Winnaars: UANL Tigres | ||||
